Paediatric schistosomiasis: last mile preparations for deploying paediatric praziquantel.

IF 7 1区 医学 Q1 PARASITOLOGY
Trends in parasitology Pub Date : 2024-08-01 Epub Date: 2024-07-19 DOI:10.1016/j.pt.2024.06.011
Francisca Mutapi, Amadou Garba, Mark Woolhouse, Paul Kazyoba
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引用次数: 0

Abstract

Schistosomiasis is the second most important parasitic disease of public health importance in Africa, affecting over 50 million children aged <5 years old. Schistosomiasis control has focused on treating school-aged children (>6 years) and adults through mass drug administration (MDA). Following the recent development of a paediatric praziquantel (PZQ) formulation for children aged <5 years, there are now concerted efforts to determine optimal and effective ways to integrate treatment of these children into national schistosomiasis control programmes. In this opinion article we outline the pathway for successful drug access, delivery, and mainstreaming of the new formulation in endemic country health systems. Effective and sustained paediatric schistosomiasis treatment is an important target of the 2030 World Health Organization (WHO) neglected tropical diseases (NTDs) roadmap.

小儿血吸虫病:部署小儿吡喹酮的最后准备工作。
血吸虫病是非洲公共卫生领域的第二大寄生虫病,通过大规模用药(MDA)影响着 5000 多万 6 岁儿童和成人。)继最近开发出适用于以下年龄段儿童的小儿吡喹酮配方(PZQ)
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来源期刊
Trends in parasitology
Trends in parasitology 医学-寄生虫学
CiteScore
14.00
自引率
3.10%
发文量
148
审稿时长
6-12 weeks
期刊介绍: Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.
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