Bacillus methanolicus: an emerging chassis for low-carbon biomanufacturing.

IF 14.3 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Trends in biotechnology Pub Date : 2024-07-19 DOI:10.1016/j.tibtech.2024.06.013

Xueting Yang, Zhaojuan Zheng, Yu Wang

引用次数: 0

Abstract

Bacillus methanolicus is a thermophilic methylotrophic bacterium that grows quickly on methanol in sea water-based media. It has been engineered for chemical bioproduction from methanol, but its efficiency needs improvement for industrialization. Synthetic biology approaches such as metabolic modeling and genome editing can reprogram B. methanolicus for low-carbon biomanufacturing.

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甲醇杆菌：低碳生物制造的新兴底盘。

甲醇杆菌（Bacillus methanolicus）是一种嗜热的甲基营养细菌，能在海水培养基中快速生长。它已被设计用于甲醇的化学生物生产，但要实现工业化，还需要提高其效率。新陈代谢建模和基因组编辑等合成生物学方法可以重新编程 B. methanolicus，使其用于低碳生物制造。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in biotechnology 工程技术-生物工程与应用微生物

CiteScore

28.60

自引率

1.20%

发文量

198

审稿时长

1 months

期刊介绍： Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).