Visible light promoted synthesis of 2-amino sugar analogues from glycals and N-aminopyridinium salts

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2024-07-17 DOI:10.1016/j.tet.2024.134144

引用次数: 0

Abstract

Herin is reported a blue light-promoted (Ir[dF(CF₃)ppy]₂(dtbpy))PF₆ catalyzed method that synthesizes the 2-amino sugar analogues from glycals, N-aminopyridinium salts and alcohol. The reactions obtained two diastereomers and the results were not influenced by the kinds of glycals. The advantage of this method is that not only different nitrogen-containing functional groups can be introduced at the C-2 position of the glycals, but also different oxygen-containing functional groups can be attached at C-1 by using methanol, tert-butanol, and water in the reaction.

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可见光促进糖醛和 N-氨基吡啶鎓盐合成 2-氨基糖类似物

Herin 报告了一种蓝光促进的 (Ir[dF(CF3)ppy]2(dtbpy))PF6 催化方法，该方法可从糖醛、N-氨基吡啶鎓盐和酒精中合成 2-氨基糖类似物。反应得到了两种非对映异构体，且结果不受糖醛种类的影响。这种方法的优点在于，不仅可以在甘氨醛的 C-2 位引入不同的含氮官能团，还可以在反应中使用甲醇、叔丁醇和水在 C-1 位连接不同的含氧官能团。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.