Comparison between botulinum toxin type A injection on masseter muscle only and additional injection on anterior belly of digastric muscle in sleep bruxism patients: A clinical trial

IF 3.1 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of oral rehabilitation Pub Date : 2024-07-18 DOI:10.1111/joor.13800

Soo-Bin Kim, You-Jin Choi, Seong Taek Kim, Hee-Jin Kim

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引用次数: 0

Abstract

Objective

This study aims to evaluate the effects on bite force and muscle thickness of the botulinum toxin (BoNT) injection for patients with sleep bruxism (SB) by comparing injections into the masseter muscle only and both the masseter and the anterior belly of the digastric muscle (ABDM) in a clinical trial.

Methods

Twelve SB patients received BoNT-A injections using US-guided techniques into the masseter muscle only (Group A), while the remaining 12 SB patients received injections into both the masseter and ABDM (Group B). Bite force and muscle thickness were measured before injection, as well as 1 and 2 months after injection.

Results

The bite force and masseter muscle thickness decreased in both Group A and Group B before injection, and at 1 and 2 months after injection. However, there was no significant difference (p > .05, repeated measures analysis of variance) between the two groups, and there was also no significant difference in ABDM thickness (p > .05, repeated measures analysis of variance).

Conclusion

This study is the first to assess the short-term effects of BoNT injected into ABDM for SB control. Results show no influence on SB reduction, suggesting the need for further research on BoNT's effectiveness in controlling intense ABDM contractions during sleep and assessing suprahyoid muscle potential impact on rhythmic masticatory muscle activity occurrence.

Abstract Image

查看原文本刊更多论文

睡眠磨牙症患者仅在颌间肌注射 A 型肉毒毒素与在掘起肌前腹额外注射 A 型肉毒毒素的比较：临床试验。

研究目的本研究旨在通过在临床试验中比较只在颌间肌和同时在颌间肌和掘腹肌前腹部（ABDM）注射肉毒杆菌毒素（BoNT）对睡眠磨牙症（SB）患者咬合力和肌肉厚度的影响：12名SB患者仅在颌间肌（A组）接受BoNT-A注射，其余12名SB患者同时在颌间肌和掘腹肌（ABDM）接受注射（B组）。注射前以及注射后 1 个月和 2 个月测量咬合力和肌肉厚度：结果：注射前、注射后 1 个月和 2 个月，A 组和 B 组的咬合力和咀嚼肌厚度均有所下降。然而，两组间无明显差异（P > .05，重复测量方差分析），ABDM 肌肉厚度也无明显差异（P > .05，重复测量方差分析）：本研究首次评估了向 ABDM 注射 BoNT 对控制 SB 的短期效果。结果表明，BoNT 对减少 SB 没有影响，这表明有必要进一步研究 BoNT 在控制睡眠期间 ABDM 强烈收缩方面的有效性，并评估舌骨上肌电位对节律性咀嚼肌活动发生的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of oral rehabilitation 医学-牙科与口腔外科

CiteScore

5.60

自引率

10.30%

发文量

116

审稿时长

4-8 weeks

期刊介绍： Journal of Oral Rehabilitation aims to be the most prestigious journal of dental research within all aspects of oral rehabilitation and applied oral physiology. It covers all diagnostic and clinical management aspects necessary to re-establish a subjective and objective harmonious oral function. Oral rehabilitation may become necessary as a result of developmental or acquired disturbances in the orofacial region, orofacial traumas, or a variety of dental and oral diseases (primarily dental caries and periodontal diseases) and orofacial pain conditions. As such, oral rehabilitation in the twenty-first century is a matter of skilful diagnosis and minimal, appropriate intervention, the nature of which is intimately linked to a profound knowledge of oral physiology, oral biology, and dental and oral pathology. The scientific content of the journal therefore strives to reflect the best of evidence-based clinical dentistry. Modern clinical management should be based on solid scientific evidence gathered about diagnostic procedures and the properties and efficacy of the chosen intervention (e.g. material science, biological, toxicological, pharmacological or psychological aspects). The content of the journal also reflects documentation of the possible side-effects of rehabilitation, and includes prognostic perspectives of the treatment modalities chosen.