Technological modes and processes to enhance the Rhodosporidium toruloides based lipid accumulation

IF 6.1 1区生物学 Q1 MICROBIOLOGY

Microbiological research Pub Date : 2024-07-16 DOI:10.1016/j.micres.2024.127840

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引用次数: 0

Abstract

Rhodosporidium toruloides has emerged as an excellent option for microbial lipid production due to its ability to accumulate up to 70 % of lipids per cell dry weight, consume multiple substrates such as glucose and xylose, and tolerate toxic compounds. Despite the potential of Rhodosporidium toruloides for high lipid yields, achieving these remains is a significant hurdle. A comprehensive review is essential to thoroughly evaluate the advancements in processes and technologies to enhance lipid production in R. toruloides. The review covers various strategies for enhancing lipid production like co-culture, adaptive evolution, carbon flux analysis, as well as different modes of fermentation. This review will help researchers to better understand the recent developments in technologies for sustainable and scalable lipid production from R. toruloides and simultaneously emphasize the need for developing an efficient and sustainable bioprocess.

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提高基于环孢红藻脂质积累的技术模式和工艺

托罗罗孢子菌（Rhodosporidium toruloides）是微生物脂质生产的绝佳选择，因为它每个细胞干重可积累高达 70% 的脂质，能消耗多种底物（如葡萄糖和木糖），并能耐受有毒化合物。尽管红孢子菌（Rhodosporidium toruloides）具有高产脂的潜力，但实现这些目标仍然是一个重大障碍。要全面评估提高环孢子丝菌脂质产量的工艺和技术的进展，必须进行全面综述。综述涵盖了提高脂质产量的各种策略，如共培养、适应性进化、碳通量分析以及不同的发酵模式。这篇综述将帮助研究人员更好地了解可持续和可扩展的褐藻脂生产技术的最新发展，同时强调开发高效和可持续生物工艺的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Microbiological research 生物-微生物学

CiteScore

10.90

自引率

6.00%

发文量

249

审稿时长

29 days

期刊介绍： Microbiological Research is devoted to publishing reports on prokaryotic and eukaryotic microorganisms such as yeasts, fungi, bacteria, archaea, and protozoa. Research on interactions between pathogenic microorganisms and their environment or hosts are also covered.