Potensi Tanaman Ganjan (Artemisia vulgaris) dalam Penyembuhan Luka Sayat pada Tikus (Sprague Dawley)

Indriana Noor Istiqomah, Mashuri, Achlish Abdillah, Laili Nur Azizah
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Abstract

Recent studies have focused on exploring natural remedies to accelerate wound healing. One such herbal plant is the Ganjan plant (Artemisia vulgaris), which contains essential oils, coumarins, flavonoids, triterpenoids, and phenolic acids, which make it a good candidate for natural remedies. This study analyzed the wound-healing potential of the Ganjan plant using a true experimental research design on 16 male Sprague Dawley rats. The rats were divided into four groups and subjected to different treatments, including a negative control group without treatment (K1), a 10% Ganjan herbal extract ointment group (K2), a 30% Ganjan herbal extract ointment group (K3), and a positive control group with 10% betadine ointment (K4). The ointments were applied once daily for 21 days or until the wounds healed, and wound area measurements were taken every three days. The results showed that the 10% and 30% Ganjan ointments effectively reduced the wound area, and there was no difference in wound contraction between 10% and 30% Ganjan ointment and 10% Betadine. The study concludes that Ganjan plant extract ointment is an effective natural remedy for wound healing and that the best results are seen in the 30% Ganjan extract ointment group.
甘姜植物(青蒿)治愈大鼠(Sprague Dawley)伤口的潜力
最近的研究重点是探索加速伤口愈合的天然疗法。Ganjan 植物(青蒿)就是其中一种草本植物,它含有精油、香豆素、类黄酮、三萜类化合物和酚酸,是天然疗法的理想选择。本研究采用真正的实验研究设计,以 16 只雄性 Sprague Dawley 大鼠为研究对象,分析了 Ganjan 植物的伤口愈合潜力。大鼠被分为四组,分别接受不同的治疗,包括未接受治疗的阴性对照组(K1)、10% 甘姜草本植物提取物软膏组(K2)、30% 甘姜草本植物提取物软膏组(K3)和含有 10%倍他丁软膏的阳性对照组(K4)。每天涂抹一次药膏,持续 21 天或直到伤口愈合,每三天测量一次伤口面积。结果显示,10% 和 30% 的甘姜软膏能有效减少伤口面积,10% 和 30% 的甘姜软膏与 10%的倍他定软膏在伤口收缩方面没有差异。研究得出结论,甘姜植物提取物软膏是一种有效的伤口愈合天然疗法,30% 甘姜提取物软膏组的效果最好。
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