Comparison of serum selenium levels in anaemic and non-anaemic Pakistani children.

Fatima Babar, Huma Abdul Shakoor, Sundas Ali, Shazia Anwar, Qurrat-ul-Ain Akhlaq, Zahra Rashid Khan
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Abstract

Objective: To compare the serum selenium levels in anemic and non-anemic Pakistani children. Study Design: Case-control Prospective study. Setting: PAEC General Hospital, Islamabad, Pakistan. Period: 1st March 2022 to 31st August 2022. Methods: A case control study was conducted wherein comparison of Selenium levels in anemic and non anaemic Pakistani children was investigated. Age, serum selenium level and haemoglobin were the quantitative variable of this study and were subjected to median and standard deviation. Severity of anemia, mean being qualitative (ordinal) variables were expressed in terms of percentages. Bar graph and tables were used to display results. Chi square test was applied to compare both the groups. Odd ratios were also calculated. A total of 60 samples from anemic and control population were selected using consecutive non-probability sampling method. Selenium levels of the serum were determined using atomic absorption spectrometry. SPSS 19 version software was used for data analysis. Results: The findings in this study indicated that 33% of cases were Selenium deficient, while 27% among controls had low Selenium levels. (p=0.57). Conclusion: This study showed no association of selenium deficiency with anaemia.
贫血和非贫血巴基斯坦儿童血清硒水平的比较。
目的比较巴基斯坦贫血儿童和非贫血儿童的血清硒水平。研究设计:病例对照前瞻性研究。研究地点:巴基斯坦伊斯兰堡 PAEC 综合医院:巴基斯坦伊斯兰堡 PAEC 综合医院。时间:2022 年 3 月 1 日至 8 月 31 日2022 年 3 月 1 日至 2022 年 8 月 31 日。研究方法进行病例对照研究,比较巴基斯坦贫血儿童和非贫血儿童的硒水平。年龄、血清硒水平和血红蛋白是本研究的定量变量,采用中位数和标准偏差表示。贫血严重程度、平均值是定性(序数)变量,用百分比表示。条形图和表格用于显示结果。采用卡方检验对两组进行比较。还计算了奇数比。采用连续非概率抽样法从贫血人群和对照人群中共抽取了 60 个样本。采用原子吸收光谱法测定血清中的硒含量。使用 SPSS 19 版软件进行数据分析。结果研究结果表明,33%的病例缺硒,而 27% 的对照组硒水平较低。(p=0.57).结论本研究表明,缺硒与贫血没有关联。
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