A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis

IF 2.9 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

ACS Chemical Health & Safety Pub Date : 2024-07-02 DOI:10.1158/0008-5472.CAN-23-1349

Brian S. White, XingYi Woo, Soner Koc, Todd B. Sheridan, Steven B. Neuhauser, Shidan Wang, Yvonne A. Evrard, Li Chen, Ali Foroughi pour, John D. Landua, R. J. Mashl, Sherri Davies, Bingliang Fang, Maria Gabriela Rosa, K. Evans, Matthew H. Bailey, Yeqing Chen, Min Xiao, Jill C. Rubinstein, Brian J. Sanderson, Michael W. Lloyd, Sergii Domanskyi, L. Dobrolecki, Maihi Fujita, J. Fujimoto, Guanghua Xiao, Ryan C. Fields, Jacqueline L Mudd, Xiaowei Xu, M. Hollingshead, S. Jiwani, Saul E. Acevedo, PDXNet consortium, B. Davis-Dusenbery, Peter N. Robinson, J. Moscow, James H. Doroshow, Nicholas Mitsiades, S. Kaochar, Chong-xian Pan, Luis G. Carvajal-Carmona, A. Welm, B. Welm, R. Govindan, Shunqiang Li, Michael A. Davies, Jack A Roth, Funda Meric-Bernstam, Yang Xie, M. Herlyn, Li Ding, Michael T. Lewis, Carol J. Bult, Dennis A. Dean, Jeffrey H. Chuang

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引用次数: 0

Abstract

A pan-cancer repository of >1,000 patient-derived xenograft hematoxylin and eosin–stained images will facilitate cancer biology investigations through histopathological analysis and contributes important model system data that expands existing human histology repositories.

查看原文本刊更多论文

带有基因组和病理注释的泛癌症患者异种移植物组织学图像库可进行深度学习分析

由超过 1,000 张源自患者的异种移植苏木精和伊红染色图像组成的泛癌症资料库将通过组织病理学分析促进癌症生物学研究，并提供重要的模型系统数据，扩展现有的人类组织学资料库。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Chemical Health & Safety PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.10

自引率

20.00%

发文量

期刊介绍： The Journal of Chemical Health and Safety focuses on news, information, and ideas relating to issues and advances in chemical health and safety. The Journal of Chemical Health and Safety covers up-to-the minute, in-depth views of safety issues ranging from OSHA and EPA regulations to the safe handling of hazardous waste, from the latest innovations in effective chemical hygiene practices to the courts'' most recent rulings on safety-related lawsuits. The Journal of Chemical Health and Safety presents real-world information that health, safety and environmental professionals and others responsible for the safety of their workplaces can put to use right away, identifying potential and developing safety concerns before they do real harm.