Gender and age clinical characteristics of patients with acute coronary syndrome

Olga V. Boulashova, E. I. Mukhitova, E. V. Khazova
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Abstract

Cardiovascular diseases remain a common cause of morbidity and mortality in populations around the world, varying in incidence by age and gender. Every year, more than 7 million people around the world are diagnosed with acute coronary syndrome, which may be the first clinical manifestation of coronary heart disease. In the ranking of mortality causes in the Russian Federation, diseases of the circulatory system occupy a leading place. The purpose of the review was to analyze the clinical characteristics and spectrum of coronary lesions of patients with acute coronary syndrome depending on age and gender. Thus, according to the results of coronary angiography, young patients with myocardial infarction were rarely accompanied by multivessel or ostial lesions of the coronary arteries, in contrast to the elderly patients. It was revealed that multivessel lesions of the coronary arteries more often characterize males, and singlevessel lesions more often characterize females. It is obvious that the prognosis of patients with acute coronary syndrome will largely depend not only on age and gender, but also on the outcome of the syndrome, the quality and scope of diagnostic and treatment procedures. This is especially important since most patients under 60 years of age are exposed to some form of systematic work load in their field of activity. The influence of polypathy, characteristic of modern cardiac patients, can be expressed to varying degrees depending on the gender and age of the patient with acute coronary syndrome. The article presents data on the short-term and long-term prognosis of patients with acute coronary syndrome, taking into account gender and age periods, including depending on the tactics of their management. Determining the clinical characteristics of patients of different ages allows to take them into account for selecting effective and safe therapy, preventing wave-like atherosclerosis as the main cause of coronary heart disease, thereby improving prognosis and survival.
急性冠状动脉综合征患者的性别和年龄临床特征
心血管疾病仍然是世界各地人群发病和死亡的常见原因,其发病率因年龄和性别而异。全世界每年有 700 多万人被诊断患有急性冠状动脉综合征,这可能是冠心病的最初临床表现。在俄罗斯联邦的死亡原因排名中,循环系统疾病占据首位。综述的目的是分析急性冠状动脉综合征患者的临床特征和冠状动脉病变谱,这取决于患者的年龄和性别。因此,根据冠状动脉造影术的结果,与老年患者相比,年轻的心肌梗死患者很少伴有冠状动脉多支血管或骨膜病变。研究发现,冠状动脉多支血管病变多见于男性,而单支血管病变多见于女性。显然,急性冠状动脉综合征患者的预后在很大程度上不仅取决于年龄和性别,还取决于综合征的结果、诊断和治疗程序的质量和范围。这一点尤为重要,因为大多数 60 岁以下的患者在其工作领域都面临着某种形式的系统性工作负担。急性冠状动脉综合征患者的性别和年龄不同,现代心脏病患者所特有的多病变的影响程度也不同。文章介绍了急性冠状动脉综合征患者的短期和长期预后数据,其中考虑到了性别和年龄段,包括对其管理策略的不同。确定不同年龄段患者的临床特征,有助于在选择有效、安全的治疗方法时考虑到这些特征,预防作为冠心病主要病因的波状动脉粥样硬化,从而改善预后和生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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