Efficacy of Atorvastatin Loaded on Nano Particles on Cryptosporidium Parvum in Experimentally Infected Mice

Abstract

: Background: Cryptosporidium parvum is an intracellular coccidial protozoa that can lead to life-threatening impacts in immunocompromised hosts. Atorvastatin may be used to treat human cryptosporidiosis. Nanomedicine developments appear promising in treatment of cryptosporidiosis. Purpose: The aim of this work is to evaluate the efficacy of atorvastatin loaded on nano-particles on treatment of cryptosporidiosis. Methods: Cryptosporidium oocysts were obtained by collection of stools from naturally infected calves. Both