Point-of-Care Assays to Trichomonas vaginalis Diagnosis: The Road So Far

Venereology Pub Date : 2024-07-11 DOI:10.3390/venereology3030009

A. Borges, Hugo Felix Perini, Eliete A. Alvin, A. C. A. Silva, Marcos Vinicius da Silva

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Abstract

Trichomonas vaginalis infection represents the most prevalent non-viral, curable parasitic sexually transmitted infection (STI) worldwide. The demand for precise and cost-effective point-of-care (POC) tests is paramount in the pursuit of STI epidemic control, ensuring expeditious patient diagnosis and therapeutic interventions. In the present study, we searched academic databases, including PubMed (US National Library of Medicine and the National Institutes of Health), Scopus, and Web of Science, employing the following keywords: “Trichomonas vaginalis”, “diagnosis”, “point-of-care tests”, and “rapid diagnosis”, to provide information about the development and effectiveness of POC tests to identify T. vaginalis. Present assays for T. vaginalis exhibit suboptimal performance, and the integration of advanced technologies, notably nanotechnologies, emerges as a formidable instrumentality for augmenting diagnostic precision while curtailing expenditure. In this review, we provide an encompassing survey of cutting-edge POC tests for T. vaginalis diagnosis and offer an outlook on future prospects in this domain.

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阴道毛滴虫诊断的护理点检测：发展之路

阴道毛滴虫感染是全球最流行的非病毒性、可治愈的寄生虫性传播感染（STI）。为了控制性传播疾病的流行，确保对患者进行快速诊断和治疗干预，对精确且具有成本效益的护理点（POC）检测的需求至关重要。在本研究中，我们检索了包括 PubMed（美国国家医学图书馆和美国国立卫生研究院）、Scopus 和 Web of Science 在内的学术数据库，并使用了以下关键词："阴道毛滴虫"、"诊断"、"护理点检测 "和 "快速诊断"，以提供有关识别阴道毛滴虫的 POC 检测的开发和有效性的信息。目前的阴道球菌检测方法性能不尽人意，而先进技术（尤其是纳米技术）的整合则是提高诊断精确度同时降低成本的有力工具。在这篇综述中，我们对用于阴道球菌诊断的尖端 POC 检测方法进行了全面调查，并对该领域的未来前景进行了展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Venereology

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