Güzide Ece Akıncı, Teymur Bornaun, Hamit Zafer Güven
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引用次数: 0
Abstract
Tubo-ovarian abscesses (TOAs) are identified as a severe and complex form of inflammatory disorder, marking an advanced progression of pelvic inflammatory disease (PID), mainly resulting from the escalation of polymicrobial infections within the female genital tract. This literature review is dedicated to elucidating the contemporary management strategies and associated complications of TOAs, amalgamating the current scholarly discourse while spotlighting the emerging therapeutic trends. The inherent complexity of TOAs, manifesting through a broad array of clinical presentations from mild symptoms to acute pelvic discomfort and fever, necessitates a comprehensive, multidisciplinary approach to achieve effective management. Traditional management has predominantly focused on antibiotic therapy, the cornerstone of initial treatment modalities. Nonetheless, this review expands on the increasing acknowledgment of minimally invasive surgical interventions, like ultrasound-guided drainage, especially in scenarios where medical therapy falters or in the presence of sizable abscesses, underscoring scenarios where antibiotic treatment may be insufficient. The discourse further explores the pivotal decision-making concerning surgical interventions, juxtaposing the benefits of abscess resolution against potential risks and complications, such as damage to adjacent structures and implications for future fertility. The review emphasizes the criticality of addressing PID’s risk factors and root causes to avert TOA development. It also ventures into the ramifications of the emergence of antibiotic-resistant bacterial strains for empirical antibiotic therapy selection, highlighting the imperative for continuous research and the adaptation of therapeutic guidelines. The complications associated with TOAs, including sepsis, infertility, and chronic pelvic pain, are meticulously examined to underscore the potential for significant long-term morbidity. Advocating for prompt diagnosis and encompassing management strategies to curtail these adverse outcomes, the review ultimately calls for intensified, quality research to refine TOA management further, particularly against the backdrop of evolving microbial resistance and the advancements in minimally invasive surgical technologies.
输卵管卵巢脓肿(TOAs)被认为是一种严重而复杂的炎症性疾病,是盆腔炎(PID)的晚期进展,主要由女性生殖道内多菌感染升级所致。这篇文献综述致力于阐明TOAs的当代治疗策略和相关并发症,综合了当前的学术论述,同时突出了新出现的治疗趋势。TOAs具有固有的复杂性,临床表现多种多样,从轻微症状到急性盆腔不适和发热,因此有必要采用综合、多学科的方法来实现有效治疗。传统的治疗方法主要集中在抗生素治疗上,这是初始治疗模式的基石。然而,本综述进一步探讨了微创手术干预的重要性,如超声引导引流术,尤其是在药物治疗无效或存在较大脓肿的情况下,强调了抗生素治疗可能不足的情况。论述进一步探讨了有关手术干预的关键决策,将脓肿解决的益处与潜在的风险和并发症(如对邻近结构的损害和对未来生育的影响)并列起来。综述强调了解决 PID 的风险因素和根本原因以避免 TOA 发展的重要性。它还探讨了抗生素耐药菌株的出现对经验性抗生素疗法选择的影响,强调了持续研究和调整治疗指南的必要性。该书仔细研究了与TOAs相关的并发症,包括败血症、不孕症和慢性盆腔疼痛,强调了长期发病的可能性。这篇综述主张及时诊断并采取全面的管理策略以减少这些不良后果,最终呼吁加强高质量的研究以进一步完善 TOA 的管理,尤其是在微生物耐药性不断发展和微创手术技术不断进步的背景下。