Oral squamous cell carcinoma: Histological grading and co relationship with cervical metastasis, depth of invasion and perineural invasion

Bazila Mansoor, Sheeba Parvez, Rimsha Ahmed, A. Khajuria
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Abstract

The aim of the study is to ascertain whether there happens to be any relation between the histological grading (according to broders system) of oral squamous cell carcinoma cases and their regional metastasis, depth of invasion and perineural invasion. Squamous cell carcinoma is known to be the most common malignancy of the oral cavity. Staging and grading of OSCC are established are the main requirements for management, because they influence risk stratification and are one of the first step towards personalized treatment. Histological grading was introduced for the first time by Broder’s for squamous cell carcinomas of lip.: This is a retrospective study of 53 patients who were diagnosed as oral squamous cell carcinomas from April 2021 to January 2023. The specimen of the cases were sent to our Department of Pathology, Acharya Shri Chandra college of medical sciences and hospital, Jammu for histopathological examination after resection.: Broder’s grading does co relate to the metastasis, depth of invasion and perineural invasion. There should be more studies at a larger level to ascertain the potential of Breslow grading.
口腔鳞状细胞癌:组织学分级及与宫颈转移、浸润深度和神经周围浸润的关系
本研究旨在确定口腔鳞状细胞癌病例的组织学分级(根据布鲁德系统)与其区域转移、浸润深度和神经周围浸润之间是否存在任何关系。众所周知,鳞状细胞癌是口腔最常见的恶性肿瘤。口腔鳞状细胞癌的分期和分级是治疗的主要要求,因为它们影响风险分层,也是实现个性化治疗的第一步。布罗德首次对唇部鳞状细胞癌进行了组织学分级:这是一项回顾性研究,研究对象是 2021 年 4 月至 2023 年 1 月期间确诊为口腔鳞状细胞癌的 53 名患者。病例标本在切除后送往查谟阿查里亚-什里-钱德拉医学院和医院病理科进行组织病理学检查:布罗德分级与转移、浸润深度和神经周围浸润无关。应在更大范围内开展更多研究,以确定布氏分级的潜力。
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