The effect of three different mydriatic eye drops on retinal vessel diameters.

IF 1.6 4区医学 Q3 OPHTHALMOLOGY

Cutaneous and Ocular Toxicology Pub Date : 2024-09-01 Epub Date: 2024-07-18 DOI:10.1080/15569527.2024.2380318

Osman Sayin, Hasan Altinkaynak

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引用次数: 0

Abstract

Purpose: To investigate the effects of topically applied 1% tropicamide, 2.5% phenylephrine and 1% cyclopentolate on retinal vessel calliper (VC) using optical coherence tomography (OCT).

Methods: Patients who came to the ophthalmology clinic for routine examination and whose OCT films were taken before dilatation and after 30 min of last dilatation drop were included in the study. 90 ophthalmologically healthy subjects were divided into 3 groups of 30 subject each according to the application of the drops as follows: Tropicamide group (Group 1), Phenylephrine group (Group 2), Cyclopentolate group (Group 3). The right eyes of the subjects were dilated with drops and the left eyes were taken as the control group. VC of retinal artery and vein passing through an area one-half to one-disc diameter from the optic disc margin were measured from OCT films. The mean of the sum of superior retinal artery (SRA) and inferior retinal artery (IRA) VC and the mean of the sum of superior retinal vein (SRV) and inferior retinal vein (IRV) VC before and after the drop were compared.

Results: There was no statistically significant change in the mean sum of SRA and IRA VC and the mean sum of SRV and IRV VC before and after dilatation drops in all three groups.

Conclusion: Dilatation drops have no statistically significant effect on retinal artery and vein VC.

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三种不同的眼药水对视网膜血管直径的影响

目的：使用光学相干断层扫描（OCT）研究局部使用1%托吡卡胺、2.5%苯肾上腺素和1%环戊丙酸对视网膜血管胼胝体（VC）的影响：研究对象包括来眼科诊所进行常规检查的患者，并在扩张前和最后一次扩张滴眼液 30 分钟后拍摄 OCT 底片。将 90 名眼科健康受试者按滴眼液的使用方法分为以下 3 组，每组 30 人：托吡卡胺组（第 1 组）、苯肾上腺素组（第 2 组）、环戊酸组（第 3 组）。受试者的右眼使用滴眼液进行散瞳，左眼作为对照组。从 OCT 片上测量通过视盘边缘二分之一至一盘直径区域的视网膜动脉和静脉的 VC。比较滴眼液前后视网膜上动脉（SRA）和视网膜下动脉（IRA）VC之和的平均值以及视网膜上静脉（SRV）和视网膜下静脉（IRV）VC之和的平均值：结果：三组患者在滴用视网膜扩张滴剂前后视网膜上动脉（SRA）和视网膜下动脉（IRA）VC的平均值之和、视网膜上静脉（SRV）和视网膜下静脉（IRV）VC的平均值之和均无明显统计学变化：结论：滴眼液对视网膜动静脉VC的影响无统计学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cutaneous and Ocular Toxicology 医学-毒理学

CiteScore

3.30

自引率

6.20%

发文量

审稿时长

1 months

期刊介绍： Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures. In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.