Ashton D Hall, Moises A Huaman, Joseph C LaPorta, Keith M Luckett
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引用次数: 0
Abstract
Tuberculosis (TB) can cause significant morbidity and mortality among solid organ transplant (SOT) recipients, including disseminated disease. Most TB cases after SOT occur in kidney transplant recipients, although data about TB in this population are sparse. Tuberculosis may present atypically in immunocompromised patients, underscoring why physicians must maintain high clinical suspicion when pertinent epidemiological risk factors are present, including birth or former residence in a country with endemic TB. We describe a unique case of disseminated TB in a 54-year-old Filipino woman who developed central nervous system tuberculoma, Pott's disease, chorioretinitis, and a perinephric fluid collection after kidney transplantation. Despite being a preventable and curable disease, TB remains a relevant and challenging infection with complex diagnostic and treatment guidelines.
结核病（TB）可导致实体器官移植（SOT）受者严重发病和死亡，包括播散性疾病。大多数 SOT 后的结核病例发生在肾移植受者身上，但有关这一人群的结核病数据却很少。结核病在免疫力低下的患者中可能表现不典型，这就说明了为什么当存在相关流行病学风险因素（包括出生或曾居住在结核病流行的国家）时，医生必须保持高度的临床怀疑。我们描述了一例独特的散发型肺结核病例，患者是一名 54 岁的菲律宾妇女，肾移植后出现中枢神经系统结核瘤、波特氏病、脉络膜视网膜炎和肾周积液。尽管结核病是一种可预防、可治愈的疾病，但它仍然是一种具有复杂诊断和治疗指南的相关性和挑战性感染。
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The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine.
The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development.
The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal.
Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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