Combined application of the traditional Chinese herbal medicine, Renvatinib, and Carrelizumab in a patient with primary liver cancer: A case report and literature review

Yan Zhu, Yaoshui Lai, Hongjie Song
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Abstract

The patient was diagnosed with primary liver cancer featuring intrahepatic metastasis (Barcelona stage B; Stage IIB), hepatitis B infection, and post-hepatitis B cirrhosis during the period of compensated liver function. Following a 7-month regimen combining traditional Chinese herbal medicine (TCHM) with Renvatinib and Carrelizumab, the patient exhibited favorable tolerability, no bleeding risks, and stable tumor progression. The effectiveness of TCHM in this case was marked by significant symptom alleviation, reduced serum molecular markers, minimized adverse reactions, and obviated surgical intervention. Blood tests displayed alpha-fetoprotein levels ranging from 8.85 to 20.65 IU/mL, with no increase in bleeding risks.

Abstract Image

在一名原发性肝癌患者身上联合应用中药瑞伐替尼和卡瑞珠单抗:病例报告和文献综述
患者被诊断为原发性肝癌,并伴有肝内转移(巴塞罗那B期;ⅡB期)、乙型肝炎感染和乙型肝炎后肝功能代偿期肝硬化。该患者在接受了为期 7 个月的传统中药与仑伐替尼、卡瑞珠单抗联合治疗后,表现出良好的耐受性,无出血风险,肿瘤进展稳定。该病例的中药疗效显著,症状明显缓解,血清分子标记物降低,不良反应减少,并避免了手术干预。血液检测显示甲胎蛋白水平在 8.85 至 20.65 IU/mL 之间,出血风险没有增加。
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