Impact of pericardial calcification on early postoperative outcomes after pericardiectomy: a retrospective observational study.

IF 1.5 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Soojin Lee, Juhyun Lee, Seohee Joo, You Kyeong Park, Kang Min Kim, Joon Chul Jung, Hyoung Woo Chang, Jae Hang Lee, Dong Jung Kim, Jun Sung Kim, Cheong Lim
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Abstract

Background: Owing to the lack of understanding of the clinical significance of pericardial calcification during pericardiectomy, whether pericardial calcification should be considered when determining the optimal timing for pericardiectomy is debatable. We aimed to investigate the effect of pericardial calcification on early postoperative outcomes in patients who underwent pericardiectomy for constrictive pericarditis.

Methods: Altogether, 44 patients who underwent pericardiectomy for constrictive pericarditis were enrolled. After excluding three patients who underwent concurrent surgeries, a total of 41 patients were categorized into two groups based on the presence of pericardial calcification as determined by preoperative computed tomography and pathological examination. Preoperative clinical and imaging characteristics, intraoperative data, and early postoperative outcomes were compared between the two groups. A multivariable analysis was performed to identify the factors associated with postoperative complications.

Results: The group with and without PC comprised 21 and 20 patients, respectively. No significant differences were observed in 30-day mortality (n = 1 [5%]) in the group with pericardial calcification and no mortality in the group without pericardial calcification (p > 0.999). Other early postoperative outcome variables did not demonstrate any significant differences between the two groups. However, the use of cardiopulmonary bypass was associated with postoperative complications (p < 0.009, odds ratio: 63.5, 95% confidence interval: 5.13-3400).

Conclusions: Pericardial calcification did not significantly affect the postoperative outcomes after pericardiectomy. Further comprehensive studies, including those with larger sample sizes and longitudinal designs, are necessary to determine whether pericardial calcification can significantly influence the timing of surgical intervention.

心包钙化对心包切除术后早期预后的影响:一项回顾性观察研究。
背景:由于对心包切除术中心包钙化的临床意义缺乏了解,在确定心包切除术的最佳时机时是否应考虑心包钙化还存在争议。我们旨在研究心包钙化对因缩窄性心包炎而接受心包切除术的患者术后早期预后的影响:共纳入44例因缩窄性心包炎接受心包切除术的患者。在排除了 3 名同时接受手术的患者后,根据术前计算机断层扫描和病理检查确定的心包钙化情况,共将 41 名患者分为两组。两组患者的术前临床和影像学特征、术中数据和术后早期疗效进行了比较。为了确定与术后并发症相关的因素,进行了多变量分析:结果:有PC和无PC组分别有21名和20名患者。有心包钙化组的 30 天死亡率(n = 1 [5%])与无心包钙化组无明显差异(P > 0.999)。其他早期术后结果变量在两组之间没有任何显著差异。不过,心肺旁路的使用与术后并发症有关(p 结论:心包钙化与术后并发症无关:心包钙化对心包切除术后的预后没有明显影响。要确定心包钙化是否会显著影响手术干预的时机,还需要进一步的综合研究,包括样本量更大和纵向设计的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Cardiothoracic Surgery
Journal of Cardiothoracic Surgery 医学-心血管系统
CiteScore
2.50
自引率
6.20%
发文量
286
审稿时长
4-8 weeks
期刊介绍: Journal of Cardiothoracic Surgery is an open access journal that encompasses all aspects of research in the field of Cardiology, and Cardiothoracic and Vascular Surgery. The journal publishes original scientific research documenting clinical and experimental advances in cardiac, vascular and thoracic surgery, and related fields. Topics of interest include surgical techniques, survival rates, surgical complications and their outcomes; along with basic sciences, pediatric conditions, transplantations and clinical trials. Journal of Cardiothoracic Surgery is of interest to cardiothoracic and vascular surgeons, cardiothoracic anaesthesiologists, cardiologists, chest physicians, and allied health professionals.
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