¹⁸F-FDG accumulation at the early onset of acute exacerbation of idiopathic interstitial pneumonia on ¹⁸F-FDG PET/CT: A case report.

IF 0.8 Q4 RESPIRATORY SYSTEM

Respirology Case Reports Pub Date : 2024-07-14 eCollection Date: 2024-07-01 DOI:10.1002/rcr2.1427

Kimitaka Akaike, Koichi Saruwatari, Shinya Sakata, Seitaro Oda, Shinya Shiraishi, Shinji Iyama, Aiko Masunaga, Yusuke Tomita, Hidenori Ichiyasu, Takuro Sakagami

{"title":"18F-FDG accumulation at the early onset of acute exacerbation of idiopathic interstitial pneumonia on 18F-FDG PET/CT: A case report.","authors":"Kimitaka Akaike, Koichi Saruwatari, Shinya Sakata, Seitaro Oda, Shinya Shiraishi, Shinji Iyama, Aiko Masunaga, Yusuke Tomita, Hidenori Ichiyasu, Takuro Sakagami","doi":"10.1002/rcr2.1427","DOIUrl":null,"url":null,"abstract":"Acute exacerbation of idiopathic interstitial pneumonias (AE-IIPs) is a disease associated with a poor prognosis in patients with IIPs. However, the specific characteristics of fluorine-18 2-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging for AE-IIPs remain unclear. Herein, we present the case of a patient with lung cancer combined with IIPs who underwent 18F-FDG PET/CT at the early onset of AE-IIPs. The scan, conducted 18 days post-bronchoscopy for lung cancer evaluation, revealed AE-IIPs before the onset of respiratory failure. New ground-glass opacities appeared, accompanied by significant 18F-FDG accumulation extending beyond these regions. To the best of our knowledge, this report represents the first assessment of 18F-FDG PET/CT images at the early onset of AE-IIPs before respiratory failure in humans. The observed features in this PET image could potentially contribute to our understanding of the pathophysiology of AE-IIPs.","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"12 7","pages":"e01427"},"PeriodicalIF":0.8000,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246593/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respirology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/rcr2.1427","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}

引用次数: 0

Abstract

Acute exacerbation of idiopathic interstitial pneumonias (AE-IIPs) is a disease associated with a poor prognosis in patients with IIPs. However, the specific characteristics of fluorine-18 2-fluoro-2-deoxy-d-glucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) imaging for AE-IIPs remain unclear. Herein, we present the case of a patient with lung cancer combined with IIPs who underwent ¹⁸F-FDG PET/CT at the early onset of AE-IIPs. The scan, conducted 18 days post-bronchoscopy for lung cancer evaluation, revealed AE-IIPs before the onset of respiratory failure. New ground-glass opacities appeared, accompanied by significant ¹⁸F-FDG accumulation extending beyond these regions. To the best of our knowledge, this report represents the first assessment of ¹⁸F-FDG PET/CT images at the early onset of AE-IIPs before respiratory failure in humans. The observed features in this PET image could potentially contribute to our understanding of the pathophysiology of AE-IIPs.

查看原文本刊更多论文

18F-FDG PET/CT 上特发性间质性肺炎急性加重早期的 18F-FDG 积累：病例报告。

特发性间质性肺炎急性加重（AE-IIPs）是一种与特发性间质性肺炎患者预后不良有关的疾病。然而，氟-18 2-氟-2-脱氧-d-葡萄糖（18F-FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）成像在 AE-IIPs 中的具体特点仍不清楚。在此，我们提供了一例肺癌合并 IIPs 患者的病例，该患者在 AE-IIPs 早期发病时接受了 18F-FDG PET/CT 扫描。患者在接受支气管镜检查评估肺癌 18 天后进行了扫描，结果显示患者在出现呼吸衰竭之前就出现了 AE-IIP。出现了新的磨玻璃不透明，并伴有明显的 18F-FDG 累积，超出了这些区域。据我们所知，该报告是首次对人类在呼吸衰竭前早期出现 AE-IIPs 时的 18F-FDG PET/CT 图像进行评估。在 PET 图像中观察到的特征可能有助于我们了解 AE-IIP 的病理生理学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Respirology Case Reports RESPIRATORY SYSTEM-

CiteScore

1.40

自引率

0.00%

发文量

178

审稿时长

8 weeks

期刊介绍： Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.