Incidence of Hospitalization due to Influenza-Associated Severe Acute Respiratory Infection During 2010–2019 in Bangladesh

IF 4.3 4区医学 Q1 INFECTIOUS DISEASES

Influenza and Other Respiratory Viruses Pub Date : 2024-07-15 DOI:10.1111/irv.13352

Mohammad Abdul Aleem, Katherine Roguski DeBord, Makhdum Ahmed, Mohammed Ziaur Rahman, Mustafizur Rahman, Md Ariful Islam, A. S. M. Alamgir, M. Salimuzzaman, Tahmina Shirin, Mohammod Jobayer Chisti, Mahmudur Rahman, Eduardo Azziz-Baumgartner, Fahmida Chowdhury, A. Danielle Iuliano

{"title":"Incidence of Hospitalization due to Influenza-Associated Severe Acute Respiratory Infection During 2010–2019 in Bangladesh","authors":"Mohammad Abdul Aleem, Katherine Roguski DeBord, Makhdum Ahmed, Mohammed Ziaur Rahman, Mustafizur Rahman, Md Ariful Islam, A. S. M. Alamgir, M. Salimuzzaman, Tahmina Shirin, Mohammod Jobayer Chisti, Mahmudur Rahman, Eduardo Azziz-Baumgartner, Fahmida Chowdhury, A. Danielle Iuliano","doi":"10.1111/irv.13352","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Global influenza-associated acute respiratory infections contribute to 3–5 million severe illnesses requiring hospitalization annually, with 90% of hospitalizations occurring among children < 5 years in developing countries. In Bangladesh, the inadequate availability of nationally representative, robust estimates of influenza-associated hospitalizations limits allocation of resources for prevention and control measures.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>This study used data from the hospital-based influenza surveillance (HBIS) system in Bangladesh from 2010 to 2019 and healthcare utilization surveys to determine hospital utilization patterns in the catchment area. We estimated annual influenza-associated hospitalization numbers and rates for all age groups in Bangladesh using WHO methods, adjusted for a 6-day-a-week enrollment schedule, selective testing of specimens from children under five, and healthcare-seeking behavior, based on the proportion of symptomatic community participants seeking healthcare within the past week. We then estimated national hospitalization rates by multiplying age-specific hospitalization rates with the corresponding annual national census population.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Annual influenza-associated hospitalization rates per 100,000 population for all ages ranged from 31 (95% CI: 27–36) in 2011 to 139 (95% CI: 130–149) in 2019. Children < 5 years old had the highest rates of influenza-associated hospitalization, ranging from 114 (95% CI: 90–138) in 2011 to 529 (95% CI: 481–578) in 2019, followed by adults aged ≥ 65 years with rates ranging from 46 (95% CI: 34–57) in 2012 to 252 (95% CI: 213–292) in 2019. The national hospitalization estimates for all ages during 2010–2019 ranged from 47,891 to 236,380 per year.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The impact of influenza-associated hospitalizations in Bangladesh may be considerable, particularly for young children and older adults. Targeted interventions, such as influenza vaccination for these age groups, should be prioritized and evaluated.</p>\n </section>\n </div>","PeriodicalId":13544,"journal":{"name":"Influenza and Other Respiratory Viruses","volume":"18 7","pages":""},"PeriodicalIF":4.3000,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/irv.13352","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Influenza and Other Respiratory Viruses","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/irv.13352","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Global influenza-associated acute respiratory infections contribute to 3–5 million severe illnesses requiring hospitalization annually, with 90% of hospitalizations occurring among children < 5 years in developing countries. In Bangladesh, the inadequate availability of nationally representative, robust estimates of influenza-associated hospitalizations limits allocation of resources for prevention and control measures.

Methods

This study used data from the hospital-based influenza surveillance (HBIS) system in Bangladesh from 2010 to 2019 and healthcare utilization surveys to determine hospital utilization patterns in the catchment area. We estimated annual influenza-associated hospitalization numbers and rates for all age groups in Bangladesh using WHO methods, adjusted for a 6-day-a-week enrollment schedule, selective testing of specimens from children under five, and healthcare-seeking behavior, based on the proportion of symptomatic community participants seeking healthcare within the past week. We then estimated national hospitalization rates by multiplying age-specific hospitalization rates with the corresponding annual national census population.

Results

Annual influenza-associated hospitalization rates per 100,000 population for all ages ranged from 31 (95% CI: 27–36) in 2011 to 139 (95% CI: 130–149) in 2019. Children < 5 years old had the highest rates of influenza-associated hospitalization, ranging from 114 (95% CI: 90–138) in 2011 to 529 (95% CI: 481–578) in 2019, followed by adults aged ≥ 65 years with rates ranging from 46 (95% CI: 34–57) in 2012 to 252 (95% CI: 213–292) in 2019. The national hospitalization estimates for all ages during 2010–2019 ranged from 47,891 to 236,380 per year.

Conclusions

The impact of influenza-associated hospitalizations in Bangladesh may be considerable, particularly for young children and older adults. Targeted interventions, such as influenza vaccination for these age groups, should be prioritized and evaluated.

Abstract Image

查看原文本刊更多论文

2010-2019 年孟加拉国流感相关严重急性呼吸道感染住院发病率。

背景：全球与流感相关的急性呼吸道感染每年导致 300-500 万例需要住院治疗的重症患者，其中 90% 的住院患者为儿童：本研究使用了孟加拉国 2010 年至 2019 年基于医院的流感监测（HBIS）系统的数据以及医疗保健使用调查，以确定集水区的医院使用模式。我们采用世界卫生组织的方法估算了孟加拉国各年龄组每年与流感相关的住院人数和住院率，并根据每周六天的登记时间表、对五岁以下儿童标本的选择性检测以及过去一周内有症状的社区参与者寻求医疗保健的比例进行了调整。然后，我们将特定年龄段的住院率乘以相应的年度全国人口普查人数，从而估算出全国的住院率：各年龄段每年每 10 万人中与流感相关的住院率从 2011 年的 31（95% CI：27-36）到 2019 年的 139（95% CI：130-149）不等。儿童结论：在孟加拉国，流感相关住院治疗的影响可能相当大，尤其是对幼儿和老年人。应优先考虑并评估有针对性的干预措施，如为这些年龄段的人群接种流感疫苗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Influenza and Other Respiratory Viruses 医学-病毒学

CiteScore

7.20

自引率

4.50%

发文量

120

审稿时长

6-12 weeks

期刊介绍： Influenza and Other Respiratory Viruses is the official journal of the International Society of Influenza and Other Respiratory Virus Diseases - an independent scientific professional society - dedicated to promoting the prevention, detection, treatment, and control of influenza and other respiratory virus diseases. Influenza and Other Respiratory Viruses is an Open Access journal. Copyright on any research article published by Influenza and Other Respiratory Viruses is retained by the author(s). Authors grant Wiley a license to publish the article and identify itself as the original publisher. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors, citation details and publisher are identified.