Digital Twins of Biological Systems: A Narrative Review

IF 2.7 Q3 ENGINEERING, BIOMEDICAL

IEEE Open Journal of Engineering in Medicine and Biology Pub Date : 2024-07-12 DOI:10.1109/OJEMB.2024.3426916

Ghufran A. Alsalloum;Nour M. Al Sawaftah;Kelly M. Percival;Ghaleb A. Husseini

引用次数: 0

Abstract

The concept of Digital Twins (DTs), software models that mimic the behavior and interactions of physical or conceptual objects within their environments, has gained traction in recent years, particularly in medicine and healthcare research. DTs technology emerges as a pivotal tool in disease modeling, integrating diverse data sources to computationally model dynamic biological systems. This narrative review explores potential DT applications in medicine, from defining DTs and their history to constructing DTs, modeling biologically relevant systems, as well as discussing the benefits, risks, and challenges in their application. The influence of DTs extends beyond healthcare and can revolutionize healthcare management, drug development, clinical trials, and various biomedical research fields

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生物系统的数字孪生：叙事回顾

数字孪生（DTs）是一种模仿物理或概念对象在其环境中的行为和交互的软件模型，其概念近年来在医学和医疗保健研究领域受到广泛关注。DTs 技术是疾病建模的重要工具，它整合了各种数据源，为动态生物系统建立计算模型。这篇叙述性综述探讨了 DTs 在医学中的潜在应用，从定义 DTs 及其历史到构建 DTs、生物相关系统建模，以及讨论其应用中的益处、风险和挑战。DTs 的影响超出了医疗保健的范畴，可为医疗保健管理、药物开发、临床试验和各种生物医学研究领域带来革命性的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Open Journal of Engineering in Medicine and Biology ENGINEERING, BIOMEDICAL-

CiteScore

9.50

自引率

3.40%

发文量

审稿时长

10 weeks

期刊介绍： The IEEE Open Journal of Engineering in Medicine and Biology (IEEE OJEMB) is dedicated to serving the community of innovators in medicine, technology, and the sciences, with the core goal of advancing the highest-quality interdisciplinary research between these disciplines. The journal firmly believes that the future of medicine depends on close collaboration between biology and technology, and that fostering interaction between these fields is an important way to advance key discoveries that can improve clinical care.IEEE OJEMB is a gold open access journal in which the authors retain the copyright to their papers and readers have free access to the full text and PDFs on the IEEE Xplore® Digital Library. However, authors are required to pay an article processing fee at the time their paper is accepted for publication, using to cover the cost of publication.