One-year outcomes in COVID-19 and non-COVID-19 intensive care unit survivors

IF 3.2 3区医学 Q2 CRITICAL CARE MEDICINE

Journal of critical care Pub Date : 2024-07-14 DOI:10.1016/j.jcrc.2024.154858

Hidde Heesakkers , Johannes G. van der Hoeven , Stijn Corsten , Inge Janssen , Esther Ewalds , Koen S. Simons , Maaike de Blauw , Thijs C.D. Rettig , Crétien Jacobs , Susanne van Santen M.D , Arjen J.C. Slooter , Margaretha C.E. van der Woude , Marieke Zegers , Mark van den Boogaard

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引用次数: 0

Abstract

Purpose

To determine differences in one-year multi-domain health outcomes in COVID-19 and non-COVID-19 intensive care unit (ICU) survivors.

Materials and methods

Adult ICU survivors treated for COVID-19 were compared to a control group consisting of survivors admitted for respiratory distress due to other causes, i.e. non-COVID-19 ARDS or pneumonia. Occurrence of physical (frailty, fatigue, physical symptoms), mental (anxiety, depression, post-traumatic stress) and cognitive symptoms, and quality of life (QoL) scores were measured, using validated questionnaires, before and one year after ICU treatment.

Results

In total, 506 COVID-19 survivors could be compared to 228 non-COVID-19 survivors. At one-year follow-up, COVID-19 ICU survivors had less physical (76.2% vs. 86.9%, p = 0.001) and mental symptoms (32.0% vs. 47.1%, p < 0.001) than the control group. Cognitive symptoms were comparable (22.5% vs. 17.2%, p = 0.12). However, compared to pre-ICU health symptoms and scores, COVID-19 survivors experienced an increase in symptom occurrence rates in all domains and a decrease in QoL, whereas the control group only experienced an increase in mental and cognitive symptoms, with a similar QoL at one-year follow-up.

Conclusions

COVID-19 ICU survivors experience equal or less health problems but a greater decline in QoL one year after ICU admission compared to non-COVID-19 ARDS or pneumonia survivors.

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COVID-19 和非 COVID-19 重症监护室幸存者的一年疗效

目的确定 COVID-19 和非 COVID-19 重症监护室 (ICU) 存活者一年多领域健康结果的差异。材料和方法将接受 COVID-19 治疗的成人 ICU 存活者与因其他原因（即非 COVID-19 ARDS 或肺炎）导致呼吸窘迫而入院的对照组进行比较。在重症监护室治疗前和治疗一年后，使用有效问卷测量了身体（虚弱、疲劳、躯体症状）、精神（焦虑、抑郁、创伤后应激）和认知症状的发生率以及生活质量（QoL）评分。结果共有 506 名 COVID-19 存活者与 228 名非 COVID-19 存活者进行了比较。在一年的随访中，COVID-19 重症监护室幸存者的躯体症状（76.2% 对 86.9%，p = 0.001）和精神症状（32.0% 对 47.1%，p < 0.001）均少于对照组。认知症状与对照组相当（22.5% 对 17.2%，p = 0.12）。然而，与入住ICU前的健康症状和评分相比，COVID-19幸存者在所有领域的症状发生率均有所上升，生活质量有所下降，而对照组仅在精神和认知症状方面有所上升，一年随访时的生活质量相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of critical care 医学-危重病医学

CiteScore

8.60

自引率

2.70%

发文量

237

审稿时长

23 days

期刊介绍： The Journal of Critical Care, the official publication of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), is a leading international, peer-reviewed journal providing original research, review articles, tutorials, and invited articles for physicians and allied health professionals involved in treating the critically ill. The Journal aims to improve patient care by furthering understanding of health systems research and its integration into clinical practice. The Journal will include articles which discuss: All aspects of health services research in critical care System based practice in anesthesiology, perioperative and critical care medicine The interface between anesthesiology, critical care medicine and pain Integrating intraoperative management in preparation for postoperative critical care management and recovery Optimizing patient management, i.e., exploring the interface between evidence-based principles or clinical insight into management and care of complex patients The team approach in the OR and ICU System-based research Medical ethics Technology in medicine Seminars discussing current, state of the art, and sometimes controversial topics in anesthesiology, critical care medicine, and professional education Residency Education.