Effects of different anesthesia methods on labor process and postpartum serum estrogen and progesterone levels in primiparas with painless labor

IF 2.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Clinics Pub Date : 2024-01-01 DOI:10.1016/j.clinsp.2024.100442

JunYan Liu , ChongLai Shi , Dan Wang , XiaoDong Cui , LiLi Geng , JingJing Cui , DongMei Sun , Zhuo Yin

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引用次数: 0

Abstract

Objective

To look into the effects of different anesthesia methods on the labor process and the expression of serum estrogen and progesterone in primiparas with painless labor.

Methods

60 primiparas receiving painless labor were selected as the research objects, and they were divided into either a Spinal & Continuous epidural anesthesia group (n = 30) or a continuous epidural anesthesia group (n = 30), anesthesia is administered using the corresponding anesthesia method. The authors compared serum estrogen and progesterone, inflammatory index expression, pain degree and neonatal health status in different periods.

Results

At T2 and T3, serum P, LH, FSH and E2 levels in the Spinal & Continuous epidural anesthesia group were signally lower than those in the Spinal & Continuous epidural anesthesia group (p < 0.05). Spinal & Continuous epidural anesthesia group harbored faster onset and longer duration of sensory block and motor block than the Continuous epidural anesthesia group (p < 0.05). SAS and SDS scores of the Spinal & Continuous epidural anesthesia group were clearly lower than those of the Continuous epidural anesthesia group (p < 0.05). VAS score and serum TNF-α, IL-6 levels of pregnant women in the Spinal & Continuous epidural anesthesia group were memorably lower than those in the Continuous epidural anesthesia group at T2 and T3 (p < 0.05). The total incidence of postoperative complications in the Spinal & Continuous epidural anesthesia group was distinctively lower than that in the Continuous epidural anesthesia group (p < 0.05).

Conclusion

Spinal anesthesia combined with continuous epidural anesthesia has a better anesthesia effect in the painless labor of primiparas, which can effectually ameliorate the labor process and the expression of serum estrogen and progesterone.

查看原文本刊更多论文

不同麻醉方法对无痛分娩初产妇分娩过程及产后血清雌激素和孕酮水平的影响。

目的方法：选取60例接受无痛分娩的初产妇作为研究对象，将其分为脊柱及连续硬膜外麻醉组（30例）或连续硬膜外麻醉组（30例），采用相应的麻醉方法进行麻醉。作者比较了不同时期的血清雌激素和孕激素、炎症指数表达、疼痛程度和新生儿健康状况：结果：在T2和T3，椎管内连续硬膜外麻醉组的血清P、LH、FSH和E2水平明显低于椎管内连续硬膜外麻醉组（P < 0.05）。与连续硬膜外麻醉组相比，脊髓和连续硬膜外麻醉组的感觉阻滞和运动阻滞发生更快，持续时间更长（P < 0.05）。脊髓连续硬膜外麻醉组的 SAS 和 SDS 评分明显低于连续硬膜外麻醉组（P < 0.05）。在T2和T3，脊柱连续硬膜外麻醉组孕妇的VAS评分和血清TNF-α、IL-6水平明显低于连续硬膜外麻醉组（P＜0.05）。脊柱和连续硬膜外麻醉组的术后并发症总发生率明显低于连续硬膜外麻醉组（P < 0.05）：结论：椎管内麻醉联合连续硬膜外麻醉对初产妇的无痛分娩有较好的麻醉效果，能有效改善产程及血清雌激素和孕激素的表达。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinics 医学-医学：内科

CiteScore

4.10

自引率

3.70%

发文量

129

审稿时长

52 days

期刊介绍： CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in the medical sciences. CLINICS complies with the policies of funding agencies which request or require deposition of the published articles that they fund into publicly available databases. CLINICS supports the position of the International Committee of Medical Journal Editors (ICMJE) on trial registration.