Racial disparities, cancer and response to oxidative stress.

Advances in cancer research Pub Date : 2019-01-01 Epub Date: 2019-04-23 DOI:10.1016/bs.acr.2019.03.012
Jie Zhang, Zhi-Wei Ye, Danyelle M Townsend, Chanita Hughes-Halbert, Kenneth D Tew
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Abstract

At the intersection of genetics, biochemistry and behavioral sciences, there is a largely untapped opportunity to consider how ethnic and racial disparities contribute to individual sensitivity to reactive oxygen species and how these might influence susceptibility to various cancers and/or response to classical cancer treatment regimens that pervasively result in the formation of such chemical species. This chapter begins to explore these connections and builds a platform from which to consider how the disciplines can be strengthened further.

种族差异、癌症和对氧化应激的反应。
在遗传学、生物化学和行为科学的交汇点上,存在着一个很大程度上尚未开发的机会,即考虑民族和种族差异如何导致个人对活性氧的敏感性,以及这些差异如何影响对各种癌症的易感性和/或对传统癌症治疗方案的反应,而传统癌症治疗方案普遍导致此类化学物质的形成。本章开始探讨这些联系,并建立一个平台,据此考虑如何进一步加强这些学科。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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