An overview of key online resources for human genomics: a powerful and open toolbox for in silico research.

IF 2.5 3区 生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Diego A Forero, Diego A Bonilla, Yeimy González-Giraldo, George P Patrinos
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引用次数: 0

Abstract

Recent advances in high-throughput molecular methods have led to an extraordinary volume of genomics data. Simultaneously, the progress in the computational implementation of novel algorithms has facilitated the creation of hundreds of freely available online tools for their advanced analyses. However, a general overview of the most commonly used tools for the in silico analysis of genomics data is still missing. In the current article, we present an overview of commonly used online resources for genomics research, including over 50 tools. This selection will be helpful for scientists with basic or intermediate skills in the in silico analyses of genomics data, such as researchers and students from wet labs seeking to strengthen their computational competencies. In addition, we discuss current needs and future perspectives within this field.

人类基因组学主要在线资源概览:用于硅学研究的强大而开放的工具箱。
高通量分子方法的最新进展带来了大量的基因组学数据。与此同时,新算法的计算实施进展也促进了数百种免费在线工具的诞生,用于对这些数据进行高级分析。然而,目前仍缺少对基因组学数据硅学分析最常用工具的总体概述。在本文中,我们概述了基因组学研究中常用的在线资源,包括 50 多种工具。对于在基因组学数据的硅学分析方面具有基础或中级技能的科学家,如湿法实验室的研究人员和寻求加强计算能力的学生,这些精选的资源将有所帮助。此外,我们还讨论了这一领域的当前需求和未来前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Briefings in Functional Genomics
Briefings in Functional Genomics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-GENETICS & HEREDITY
CiteScore
6.30
自引率
2.50%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Briefings in Functional Genomics publishes high quality peer reviewed articles that focus on the use, development or exploitation of genomic approaches, and their application to all areas of biological research. As well as exploring thematic areas where these techniques and protocols are being used, articles review the impact that these approaches have had, or are likely to have, on their field. Subjects covered by the Journal include but are not restricted to: the identification and functional characterisation of coding and non-coding features in genomes, microarray technologies, gene expression profiling, next generation sequencing, pharmacogenomics, phenomics, SNP technologies, transgenic systems, mutation screens and genotyping. Articles range in scope and depth from the introductory level to specific details of protocols and analyses, encompassing bacterial, fungal, plant, animal and human data. The editorial board welcome the submission of review articles for publication. Essential criteria for the publication of papers is that they do not contain primary data, and that they are high quality, clearly written review articles which provide a balanced, highly informative and up to date perspective to researchers in the field of functional genomics.
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