Chaperones in concert: Orchestrating co-translational protein folding in the cell

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2024-07-11 DOI:10.1016/j.molcel.2024.06.018

Bob Schiffrin, Antonio N. Calabrese

引用次数: 0

Abstract

In this issue of Molecular Cell, Roeselová et al.¹ provide insights into co-translational folding of a multidomain protein in bacteria, revealing how the chaperones Trigger Factor, DnaJ, and DnaK work together to facilitate the folding of nascent chains.

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伴侣协同作用：协调细胞中蛋白质的共翻译折叠

在本期《分子细胞》（Molecular Cell）杂志上，Roeselová 等人1 深入研究了细菌中一种多链蛋白的共翻译折叠，揭示了伴侣触发因子（Trigger Factor）、DnaJ 和 DnaK 如何共同促进新生链的折叠。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.