Evaluating the Effectiveness of the COPD Assessment Test (CAT) in Screening for Chronic Obstructive Pulmonary Disease

IF 2.8 3区 医学 Q1 Medicine
Nadia Al Wachami, Karima Boumendil, Maryem Arraji, Younes Iderdar, Yassmine Mourajid, Nadia Ghosne, Ali Benmoussa, Mohamed Khalis, Amal Korrida, Fatima Zahra Laamiri, Halima Lajane, Mohamed Lahbib Louerdi, Saad El Madani, Mohamed Chahboune
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Abstract

Background: Chronic obstructive pulmonary disease (COPD) is a major public health problem that remains largely under-diagnosed, mainly due to the under-use of spirometry to establish the diagnosis. The aim of this study is to evaluate the effectiveness of the Moroccan Arabic dialect version of the COPD Assessment Test (CAT) in screening for COPD.
Methods: This was a cross-sectional study carried out in primary care facilities in Morocco, involving participants aged 40 and over. The performance of CAT in detecting cases of COPD was measured with reference to the results of spirometry, considered to be the gold Standard.
Results: A total of 477 participants were included in the study. The prevalence of COPD was 6.7%. Internal consistency of the Moroccan Arabic dialect version of the CAT was high, with a Cronbach’s alpha of 0.89. The total score of the CAT and of each item was significantly higher in subjects with COPD than in those without (P=0.000). Significantly negative correlations were found between CAT total score and FEV1 (r = − 0.33, p=0.000), CAT and FVC (r = − 0.22, p=0.000), CAT and FEV1/FVC ratio (r = − 0.22, p=0.000). The receiver operating characteristic curve showed an area under the curve of 0.93. A CAT score of 10 was the optimal cut-off value for COPD screening, with a sensitivity, specificity, positive predictive value, and negative predictive value of 78.1%, 93.9%, 48.1% and 98.4%, respectively.
Conclusion: The results of the present study showed that the CAT could be used as a screening tool for COPD. The use of this tool by healthcare professionals in primary care settings will improve and promote early diagnosis of this chronic disease.

评估慢性阻塞性肺病评估测试(CAT)在筛查慢性阻塞性肺病中的效果
背景:慢性阻塞性肺病(COPD)是一个重大的公共卫生问题,但在很大程度上仍未得到充分诊断,这主要是由于未充分利用肺活量测定来确定诊断。本研究旨在评估摩洛哥阿拉伯语方言版慢性阻塞性肺病评估测试(CAT)在筛查慢性阻塞性肺病方面的有效性:这是一项在摩洛哥初级医疗机构开展的横断面研究,参与者年龄在 40 岁及以上。CAT在检测慢性阻塞性肺病病例方面的表现参照了被视为黄金标准的肺活量测定结果:研究共纳入了 477 名参与者。慢性阻塞性肺病的发病率为 6.7%。摩洛哥阿拉伯语方言版 CAT 的内部一致性很高,Cronbach's alpha 为 0.89。患有慢性阻塞性肺病的受试者 CAT 总分和每个项目的总分都明显高于未患有慢性阻塞性肺病的受试者(P=0.000)。CAT总分与FEV1(r = - 0.33,P=0.000)、CAT与FVC(r = - 0.22,P=0.000)、CAT与FEV1/FVC比值(r = - 0.22,P=0.000)之间呈显著负相关。接收者操作特征曲线显示曲线下面积为 0.93。CAT得分10是慢性阻塞性肺病筛查的最佳临界值,其敏感性、特异性、阳性预测值和阴性预测值分别为78.1%、93.9%、48.1%和98.4%:本研究结果表明,CAT 可用作慢性阻塞性肺病的筛查工具。基层医疗机构的医护人员使用该工具将改善并促进对慢性阻塞性肺病的早期诊断。
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来源期刊
CiteScore
5.10
自引率
10.70%
发文量
372
审稿时长
16 weeks
期刊介绍: An international, peer-reviewed journal of therapeutics and pharmacology focusing on concise rapid reporting of clinical studies and reviews in COPD. Special focus will be given to the pathophysiological processes underlying the disease, intervention programs, patient focused education, and self management protocols. This journal is directed at specialists and healthcare professionals
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