不断发展的嵌合抗原受体(CAR)T 细胞疗法虽然前景广阔,但仍需要更全面的成像方法来提高治疗效果,并跟踪患者体内和体外的细胞贩运情况。本综述探讨了 PET 成像在 CAR T 细胞运输中的应用,以及如何优化其治疗效果。使用各种放射性同位素的 PET 成像技术有望评估 CAR T 细胞在宿主体内的相互作用,从而促进改善患者预后的策略。随着这项技术的发展,预计会有更多的创新战略来简化免疫治疗效果的评估。
PET ClinicsRADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
5.70
自引率
3.80%
发文量
78
期刊介绍:
As the clinical applications of positron emission tomography (PET) increase, the new PET Clinics brings together the combined expertise of leading authorities in the field to provide you incisive clinical reviews on advances in the use of PET and combined PET/CT. Published quarterly, PET Clinics provides concise, practical guidance on the clinical issues you face every day. It examines PET is effectiveness in cancer diagnosis and staging, as well as exploring PET is usefulness in the areas of dementia, myocardial viability, and other conditions. Full-color images featured throughout. Topics covered include Breast Cancer, Alzheimer is Disease and Dementia, Lymphoma, Lung Cancer, Cardiology, Pediatric Applications, Infection and Inflammation.