Psychopharmacology Review for Eating Disorders Among Children, Adolescents, and Adults.

Focus (American Psychiatric Publishing) Pub Date : 2024-07-01 Epub Date: 2024-06-28 DOI:10.1176/appi.focus.20230043
Zinnia Ali, Jennifer Couturier
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Abstract

This article reviews the latest research on pharmacological management of eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and avoidant/restrictive food intake disorder. Recent literature for both youth and adult populations obtained through a PubMed search was included. American Psychiatric Association guidelines, National Institute for Health and Care Excellence guidelines, Canadian practice guidelines, and World Federation of Societies of Biological Psychiatry guidelines were also included. First-line recommendations were focused on therapy because the evidence for medication management of eating disorders continues to be limited. Some limited evidence was found for antipsychotic use for AN, selective serotonin reuptake inhibitors and topiramate use for BN, and stimulant and topiramate use for BED. Further medication trials are needed to help with complex eating disorder presentations in adults and youth.

儿童、青少年和成年人饮食失调的精神药理学综述》。
本文回顾了有关饮食失调症(包括神经性厌食症(AN)、神经性贪食症(BN)、暴饮暴食症(BED)和回避性/限制性食物摄入失调症)药物治疗的最新研究。通过 PubMed 搜索获得的有关青少年和成人的最新文献均包括在内。此外,还包括美国精神病学协会指南、美国国家健康与护理卓越研究所指南、加拿大实践指南以及世界生物精神病学协会联合会指南。一线建议主要集中在治疗方面,因为饮食失调症的药物治疗证据仍然有限。一些有限的证据显示,抗精神病药物可用于AN,选择性5-羟色胺再摄取抑制剂和托吡酯可用于BN,兴奋剂和托吡酯可用于BED。需要进一步开展药物试验,以帮助治疗成人和青少年的复杂饮食失调症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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