Notable Visualization of the Gallbladder on a 99mTc-MDP SPECT/CT Bone Scintigraphy in a Case of Brucellosis.

IF 0.4 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Indian Journal of Nuclear Medicine Pub Date : 2024-03-01 Epub Date: 2024-05-29 DOI:10.4103/ijnm.ijnm_18_24
Mahdi Haghighatafshar, Farinaz Farhoudi, Seyed Mohammad Entezarmahdi
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引用次数: 0

Abstract

Comprehension of the typical distribution pattern of 99mTc-methylenediphosphonate (MDP) is crucial for precise interpretation of bone scintigraphy. The presence of nonskeletal activity is predominantly confined to the kidneys and bladder, attributed to the standard renal excretion of 99mTc-MDP. We discuss a 70-year-old woman with a known case of brucellosis using rifampin, doxycycline, trimethoprim/sulfamethoxazole (co-trimoxazole), and ciprofloxacin for the past 8 months. Anterior and posterior aspects of the whole-body bone scan showed diffuse increased uptake in the bodies of L2 and L3 vertebrae and related intervertebral disks. However, unexpected uptake is noted in the right upper quadrant in the region of the gallbladder. Radiochemical impurities did not show during radiopharmaceutical (MDP) quality control, and the other patients showed normal distribution. This gallbladder uptake may be attributed to the altered distribution of the radiotracer and/or gallbladder injury caused by the administration of antibiotic therapy.

在一例布鲁氏菌病病例中,99m锝-MDP SPECT/CT 骨闪烁扫描显示胆囊明显可见。
了解 99mTc 亚甲基二膦酸盐(MDP)的典型分布模式对于准确解释骨闪烁成像至关重要。非骨骼活性主要局限于肾脏和膀胱,这是因为 99mTc-MDP 经肾脏排泄。我们讨论的是一名 70 岁女性,她已知患有布鲁氏菌病,过去 8 个月一直在使用利福平、强力霉素、三甲双胍/磺胺甲恶唑(联合三唑)和环丙沙星。全身骨扫描的前后两侧显示,L2 和 L3 椎体及相关椎间盘的摄取量弥漫性增加。然而,右上腹胆囊区域出现了意外的摄取。在放射性药物(MDP)质控过程中未发现放射化学杂质,其他患者也显示出正常分布。胆囊摄取可能是由于放射性示踪剂的分布改变和/或使用抗生素治疗导致胆囊损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Indian Journal of Nuclear Medicine
Indian Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
0.70
自引率
0.00%
发文量
46
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