{"title":"Natural Selection Across Three Generations of Americans.","authors":"David Hugh-Jones, Tobias Edwards","doi":"10.1007/s10519-024-10189-8","DOIUrl":null,"url":null,"abstract":"<p><p>We investigate natural selection on polygenic scores in the contemporary US, using the Health and Retirement Study. Across three generations, scores which correlate negatively (positively) with education are selected for (against). However, results only partially support the economic theory of fertility as an explanation for natural selection. The theory predicts that selection coefficients should be stronger among low-income, less educated, unmarried and younger parents, but these predictions are only half borne out: coefficients are larger only among low-income parents and unmarried parents. We also estimate effect sizes corrected for noise in the polygenic scores. Selection for some health traits is similar in magnitude to that for cognitive traits.</p>","PeriodicalId":8715,"journal":{"name":"Behavior Genetics","volume":" ","pages":"405-415"},"PeriodicalIF":2.6000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavior Genetics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10519-024-10189-8","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"BEHAVIORAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
We investigate natural selection on polygenic scores in the contemporary US, using the Health and Retirement Study. Across three generations, scores which correlate negatively (positively) with education are selected for (against). However, results only partially support the economic theory of fertility as an explanation for natural selection. The theory predicts that selection coefficients should be stronger among low-income, less educated, unmarried and younger parents, but these predictions are only half borne out: coefficients are larger only among low-income parents and unmarried parents. We also estimate effect sizes corrected for noise in the polygenic scores. Selection for some health traits is similar in magnitude to that for cognitive traits.
我们利用 "健康与退休研究"（Health and Retirement Study）调查了当代美国多基因分数的自然选择。在三代人中，与教育呈负相关（正相关）的分数被选择（反对）。然而，结果仅部分支持生育率经济理论对自然选择的解释。根据该理论的预测，低收入、受教育程度较低、未婚和年轻父母的选择系数应该更大，但这些预测只得到了一半的证实：只有低收入父母和未婚父母的系数更大。我们还估算了修正多基因评分噪声后的效应大小。某些健康特征的选择程度与认知特征的选择程度相似。
期刊介绍：
Behavior Genetics - the leading journal concerned with the genetic analysis of complex traits - is published in cooperation with the Behavior Genetics Association. This timely journal disseminates the most current original research on the inheritance and evolution of behavioral characteristics in man and other species. Contributions from eminent international researchers focus on both the application of various genetic perspectives to the study of behavioral characteristics and the influence of behavioral differences on the genetic structure of populations.
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