A mechano-diffusion characterization platform for probing strain-programmable nanoparticle diffusion in hydrogels

IF 1.8 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
Chuwei Ye, Shaoting Lin
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引用次数: 0

Abstract

Nanoparticle diffusion is a fundamental process that ubiquitously exists in life science and engineering technology. Recent studies demonstrate the potential of harnessing mechanical deformation to program nanoparticle diffusion in hydrogels, offering an expanded spectrum of nanoparticle diffusivities with precise and on-demand control. Here, we develop a mechano-diffusion characterization platform (MDCP) that integrates a mechanical system to apply controlled tension and torsion loads to deformable mediums, and an imaging system to capture spatiotemporal diffusion profiles of nanoparticles. Employing the MDCP, we study the impact of mechanical deformation on nanoparticle diffusion in hydrogels subjected to controlled stress states and loading rates.

Graphical abstract

Abstract Image

用于探测水凝胶中应变可编程纳米粒子扩散的机械扩散表征平台
纳米粒子扩散是生命科学和工程技术中普遍存在的一个基本过程。最近的研究表明,利用机械变形来控制纳米粒子在水凝胶中的扩散具有很大的潜力,它能通过精确的按需控制来扩大纳米粒子的扩散范围。在这里,我们开发了一个机械扩散表征平台(MDCP),该平台集成了一个机械系统,可对可变形介质施加受控拉力和扭力载荷,以及一个成像系统,可捕捉纳米粒子的时空扩散曲线。利用 MDCP,我们研究了机械变形对纳米粒子在受控应力状态和加载速率的水凝胶中扩散的影响。
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来源期刊
MRS Communications
MRS Communications MATERIALS SCIENCE, MULTIDISCIPLINARY-
CiteScore
2.60
自引率
10.50%
发文量
166
审稿时长
>12 weeks
期刊介绍: MRS Communications is a full-color, high-impact journal focused on rapid publication of completed research with broad appeal to the materials community. MRS Communications offers a rapid but rigorous peer-review process and time to publication. Leveraging its access to the far-reaching technical expertise of MRS members and leading materials researchers from around the world, the journal boasts an experienced and highly respected board of principal editors and reviewers.
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