Navigating nephrotoxic waters: A comprehensive overview of contrast-induced acute kidney injury prevention.

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Panagiotis Theofilis, Rigas Kalaitzidis
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引用次数: 0

Abstract

Contrast-induced acute kidney injury (CI-AKI) is the third leading cause of acute kidney injury deriving from the intravascular administration of contrast media in diagnostic and therapeutic procedures and leading to longer in-hospital stay and increased short and long-term mortality. Its pathophysiology, although not well-established, revolves around medullary hypoxia paired with the direct toxicity of the substance to the kidney. Critically ill patients, as well as those with pre-existing renal disease and cardiovascular comorbidities, are more susceptible to CI-AKI. Despite the continuous research in the field of CI-AKI prevention, clinical practice is based mostly on periprocedural hydration. In this review, all the investigated methods of prevention are presented, with an emphasis on the latest evidence regarding the potential of RenalGuard and contrast removal systems for CI-AKI prevention in high-risk individuals.

在肾毒性水域中航行:造影剂诱发急性肾损伤预防综合概述。
造影剂诱发的急性肾损伤(CI-AKI)是诊断和治疗过程中血管内使用造影剂导致急性肾损伤的第三大主要原因,会导致住院时间延长、短期和长期死亡率上升。尽管其病理生理学尚未得到很好的证实,但它是围绕髓质缺氧和物质对肾脏的直接毒性而产生的。重症患者以及原有肾脏疾病和心血管并发症的患者更容易发生 CI-AKI。尽管在 CI-AKI 预防领域的研究仍在继续,但临床实践主要基于围手术期水化。本综述介绍了所有研究过的预防方法,重点是有关 RenalGuard 和造影剂清除系统在预防高危人群 CI-AKI 方面潜力的最新证据。
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来源期刊
World journal of radiology
World journal of radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
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8.00%
发文量
35
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