A case of relieving thymoma after conservative management of anti-gamma-aminobutyric acid receptor type A encephalitis.

IF 2.3 3区医学 Q3 ONCOLOGY

Thoracic Cancer Pub Date : 2024-08-01 Epub Date: 2024-07-10 DOI:10.1111/1759-7714.15402

Yanmei Li, Ning Xie

引用次数: 0

Abstract

Anti-gamma-aminobutyric acid receptor type A (GABAA) encephalitis is a relatively rare autoimmune encephalitis, and often associated with thymoma. Here, a 44-year-old female was diagnosed as having a thymoma with autoimmune encephalitis. At 4-month follow-up she was without recurrence of symptoms after treatment with methylprednisolone pulse therapy and immunotherapy. This case report provides a reference for the identification of this type of paraneoplastic encephalitis and for a therapeutic schedule. It also highlights that conservative treatment may be effective for patients with a tumor and GABAA encephalitis.

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一例抗γ-氨基丁酸受体 A 型脑炎保守治疗后缓解的胸腺瘤。

抗γ-氨基丁酸受体A型（GABAA）脑炎是一种相对罕见的自身免疫性脑炎，通常与胸腺瘤有关。这里有一名 44 岁的女性被诊断为胸腺瘤合并自身免疫性脑炎。经过甲基强的松龙脉冲疗法和免疫疗法治疗后，她在 4 个月的随访中症状没有复发。本病例报告为识别这种副肿瘤性脑炎和制定治疗方案提供了参考。报告还强调，保守治疗对患有肿瘤和 GABAA 脑炎的患者可能有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Thoracic Cancer ONCOLOGY-RESPIRATORY SYSTEM

CiteScore

5.20

自引率

3.40%

发文量

439

审稿时长

2 months

期刊介绍： Thoracic Cancer aims to facilitate international collaboration and exchange of comprehensive and cutting-edge information on basic, translational, and applied clinical research in lung cancer, esophageal cancer, mediastinal cancer, breast cancer and other thoracic malignancies. Prevention, treatment and research relevant to Asia-Pacific is a focus area, but submissions from all regions are welcomed. The editors encourage contributions relevant to prevention, general thoracic surgery, medical oncology, radiology, radiation medicine, pathology, basic cancer research, as well as epidemiological and translational studies in thoracic cancer. Thoracic Cancer is the official publication of the Chinese Society of Lung Cancer, International Chinese Society of Thoracic Surgery and is endorsed by the Korean Association for the Study of Lung Cancer and the Hong Kong Cancer Therapy Society. The Journal publishes a range of article types including: Editorials, Invited Reviews, Mini Reviews, Original Articles, Clinical Guidelines, Technological Notes, Imaging in thoracic cancer, Meeting Reports, Case Reports, Letters to the Editor, Commentaries, and Brief Reports.