R E Feinstein, E J Gimeno, M el-Salhy, E Wilander, G Walinder
{"title":"Evidence of C-cell destruction in the thyroid gland of mice exposed to high 131I doses.","authors":"R E Feinstein, E J Gimeno, M el-Salhy, E Wilander, G Walinder","doi":"10.3109/02841868609136405","DOIUrl":null,"url":null,"abstract":"<p><p>The parafollicular cells of the thyroid gland were visualized by means of the Sevier-Munger silver technique in normal mice and in mice receiving 131I in amounts sufficient to completely destroy the thyroid tissue. The destruction of the C-cells was observed in all 131I injected mice, and no histologic signs of recovery were seen during a period of 40 days following the treatment.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 3","pages":"199-202"},"PeriodicalIF":0.0000,"publicationDate":"1986-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136405","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica. Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841868609136405","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
The parafollicular cells of the thyroid gland were visualized by means of the Sevier-Munger silver technique in normal mice and in mice receiving 131I in amounts sufficient to completely destroy the thyroid tissue. The destruction of the C-cells was observed in all 131I injected mice, and no histologic signs of recovery were seen during a period of 40 days following the treatment.