Capabilities of Diffusion Spectroscopy with Spatial Resolution in Determining the Hydration and Parameters of the Microvasculature of Biotissues

IF 0.8 4区 化学 Q4 SPECTROSCOPY
V. A. Firago
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引用次数: 0

Abstract

The capabilities of spectroscopy with spatial resolution when determining the optical properties and parameters of the microvasculature of the circulatory system of surface tissues are demonstrated using specific examples of recording and processing the spectral-spatial profiles of local diffuse reflection of light by tissues of the human hand. The heterogeneity of tissue properties caused by individual distribution of vessels and chromophore concentration gradients at the investigated point of the body in addition to inadequacies of the used calculation model due to poorly studied absorption indices of the main chromophores of exsanguinated and dehydrated subcutaneous tissue are shown to contribute most to the scatter of the obtained results. A technique for recording spectral-spatial profiles and their two-stage processing is presented. Its capabilities and disadvantages are discussed. Prospective application of diffuse reflectance spectroscopy with spatial resolution to controlling the hydration of surface tissues during treatment of their inflammation and edema is shown.

具有空间分辨率的扩散光谱法在确定生物组织微血管的水合度和参数方面的能力
通过记录和处理人体手部组织对光的局部漫反射的光谱空间分布图的具体实例,展示了空间分辨率光谱学在确定体表组织循环系统微血管的光学特性和参数方面的能力。由于血管的个体分布和身体调查点的发色团浓度梯度造成的组织特性的异质性,以及由于对放血和脱水皮下组织的主要发色团的吸收指数研究不足而造成的计算模型的不足,都是造成所获结果分散的主要原因。介绍了一种记录光谱空间剖面及其两阶段处理的技术。对其功能和缺点进行了讨论。展示了具有空间分辨率的漫反射光谱技术在治疗炎症和水肿期间控制表面组织水合作用的前瞻性应用。
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来源期刊
CiteScore
1.30
自引率
14.30%
发文量
145
审稿时长
2.5 months
期刊介绍: Journal of Applied Spectroscopy reports on many key applications of spectroscopy in chemistry, physics, metallurgy, and biology. An increasing number of papers focus on the theory of lasers, as well as the tremendous potential for the practical applications of lasers in numerous fields and industries.
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