Unraveling the function of FGF signaling in human hypoblast specialization.

Hao Wu, Jinglei Zhai, Hongmei Wang
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Abstract

Dattani et al.1 developed a method for inducing hypoblast-like cells from human naive pluripotent stem cells. They elucidated the requirement for FGF signaling in human hypoblast specialization at a specific time window, which was previously controversial.

揭示 FGF 信号在人类低分化母细胞特化过程中的功能。
Dattani 等人1 开发了一种从人类幼稚多能干细胞中诱导出低分化母细胞样细胞的方法。他们阐明了在特定的时间窗口内,人的低母细胞特化需要 FGF 信号,而这在以前是有争议的。
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