Effect of altrenogest treatment before weaning on reproductive performance and production efficiency in primiparous and multiparous sows.

IF 3 2区 农林科学 Q1 VETERINARY SCIENCES
Kexiong Liu, Xiaoling Xu, Yuqing Song, Linli Xiao, Junhui Wen, Haiquan Ding, Shuxin Zhao, Dongliang Qiao, Bo Zhang, Aihua Niu, Jiahua Bai, Yan Liu
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引用次数: 0

Abstract

Background: Most sows will experience negative energy balance during lactation resulting in impaired follicular development. This study aimed to treat 28-day lactating sows with altrenogest (ALT) to suppress follicle enlargement during lactation, and to assess the estrus and reproductive performance post-weaning.

Methods: In this study, we conducted two trials. In trial 1, we monitored the follicular development of lactating sows including 10 primiparous sows and 10 multiparous sows during the whole lactation to confirm the ALT administration time. In trial 2, a total of 42 primiparous and 111 multiparous sows were allocated to three treatments: Ctrl (control group, n = 51): no treatment; TAI (timed artificial insemination group, n = 51): sows were injected with equine chorionic gonadotropin (eCG) after weaning 24 h and gonadotropin-releasing hormone (GnRH) when they expressed estrus; and AT-TAI (ALT treatment-timed artificial insemination group, n = 51): base on the process of TAI group, the sows were fed with 20 mg ALT per day before weaning 10 days. All sows were artificially inseminated twice at 12 h and 36 h after estrus. The follicle size changes and serum hormone levels were explored in this process.

Results: Although the follicle size of multiparous sows was larger than primiparous sows during the whole lactation (P < 0.05), similar change trends of follicle size were observed in primiparous and multiparous sows. Meanwhile, the FSH, LH and E2 levels of multiparous sows were higher than primiparous sows. The ALT treatment significantly inhibits the increase in follicle size (P < 0.05) and reduces the serum levels of FSH, LH and E2 (P > 0.05). Additionally, ALT treatment increases estrus concentration and the preovulatory follicle size (P < 0.05), meanwhile, it delays the weaning-to-estrus interval (WEI, P < 0.001). However, the estrus rate, pregnancy rate, total pigs born and born alive did not differ between treatments (P > 0.05).

Conclusions: There were significant differences in the size of follicles in the lactation between primiparous and multiparous sows. ALT treatment during the last ten days of lactation concentrated estrus expression leading to higher work efficiency of breeder in batch production, however, with no improvement in reproductive performance.

断奶前使用阿替孕酮对初产母猪和多产母猪繁殖性能和生产效率的影响
背景:大多数母猪在哺乳期会出现能量负平衡,导致卵泡发育受损。本研究旨在用阿替孕酮(ALT)治疗28天泌乳母猪,以抑制泌乳期卵泡增大,并评估断奶后的发情和繁殖性能:在这项研究中,我们进行了两项试验。在试验 1 中,我们监测了包括 10 头初产母猪和 10 头多产母猪在内的哺乳母猪在整个哺乳期的卵泡发育情况,以确定 ALT 的用药时间。在试验 2 中,共有 42 头初产母猪和 111 头多胎母猪被分配到三种处理中:Ctrl(对照组,n = 51):不进行任何处理;TAI(定时人工授精组,n = 51):在母猪断奶24小时后注射马绒毛膜促性腺激素(eCG),并在母猪发情时注射促性腺激素释放激素(GnRH);AT-TAI(ALT处理-定时人工授精组,n = 51):在TAI组处理的基础上,在母猪断奶10天前每天饲喂20毫克ALT。所有母猪分别在发情后 12 h 和 36 h 进行两次人工授精。在此过程中对卵泡大小变化和血清激素水平进行了研究:结果:虽然多胎母猪在整个泌乳期的卵泡大小大于初产母猪(P 2),但多胎母猪的血清激素水平高于初产母猪。ALT 处理可明显抑制卵泡体积的增加(P 2(P > 0.05))。此外,ALT 处理可增加发情浓度和排卵前卵泡大小(P 0.05):初产母猪和多产母猪的泌乳期卵泡大小存在明显差异。泌乳期最后十天的 ALT 处理可集中发情,从而提高种猪在批量生产中的工作效率,但对繁殖性能没有改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Porcine Health Management
Porcine Health Management Veterinary-Food Animals
CiteScore
5.40
自引率
5.90%
发文量
49
审稿时长
14 weeks
期刊介绍: Porcine Health Management (PHM) is an open access peer-reviewed journal that aims to publish relevant, novel and revised information regarding all aspects of swine health medicine and production.
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