Assessing inter and intrafraction uncertainties in adult brain cancer patients using 2D/3D kV and CBCT imaging

Abstract

Method

2D/3D kV imaging and CBCT data using 6 degrees of freedom (6DoF) were compared to evaluate inter and intrafraction motion.

Results

Results showed that intrafraction errors were low and interfraction levels were within institutional protocols.

Conclusion

Confidence was given to use low dose 2D/3D kV imaging to confirm daily patient set up errors, and to use pre-treatment CBCT only once weekly for additional imaging information.

Implications for practice

Further research is necessary to assess other uncertainties, to enable the calculation of a margin and determining the feasibility of further reduction of this.