Definition and Epidemiology of Sepsis.

IF 2.3 3区 医学 Q2 CRITICAL CARE MEDICINE
Pietro Arina, Daniel A Hofmaenner, Mervyn Singer
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引用次数: 0

Abstract

Here we review the epidemiology of sepsis, focusing on its definition, incidence, and mortality, as well as the demographic insights and risk factors that influence its occurrence and outcomes. We address how age, sex, and racial/ethnic disparities impact upon incidence and mortality rates. Sepsis is more frequent and severe among the elderly, males, and certain racial and ethnic groups. Poor socioeconomic status, geographic location, and pre-existing comorbidities also elevate the risk of developing and dying from sepsis. Seasonal variations, with an increased incidence during winter months, is also apparent. We delve into the predictive value of disease severity scores such as the Sequential Organ Failure Assessment score. We also highlight issues relating to coding and administrative data that can generate erroneous and misleading information, and the need for greater consistency. The Sepsis-3 definitions, offering more precise clinical criteria, are a step in the right direction. This overview will, we hope, facilitate understanding of the multi-faceted epidemiological characteristics of sepsis and current challenges.

败血症的定义和流行病学。
在此,我们回顾了败血症的流行病学,重点关注其定义、发病率和死亡率,以及影响其发生和结果的人口学见解和风险因素。我们探讨了年龄、性别和种族/民族差异对发病率和死亡率的影响。败血症在老年人、男性以及某些种族和民族群体中更为常见和严重。不良的社会经济状况、地理位置和原有的合并症也会增加患败血症和死于败血症的风险。季节性变化也很明显,冬季发病率增加。我们深入探讨了疾病严重程度评分(如序贯器官衰竭评估评分)的预测价值。我们还强调了与编码和管理数据有关的问题,这些问题可能会产生错误和误导性信息,因此需要加强一致性。败血症-3 定义提供了更精确的临床标准,是朝着正确方向迈出的一步。我们希望这一概述将有助于理解败血症多方面的流行病学特征和当前的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
0.00%
发文量
87
审稿时长
6-12 weeks
期刊介绍: The journal focuses on new diagnostic and therapeutic procedures, laboratory studies, genetic breakthroughs, pathology, clinical features and management as related to such areas as asthma and other lung diseases, critical care management, cystic fibrosis, lung and heart transplantation, pulmonary pathogens, and pleural disease as well as many other related disorders.The journal focuses on new diagnostic and therapeutic procedures, laboratory studies, genetic breakthroughs, pathology, clinical features and management as related to such areas as asthma and other lung diseases, critical care management, cystic fibrosis, lung and heart transplantation, pulmonary pathogens, and pleural disease as well as many other related disorders.
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