Fatigue in multiple sclerosis: can we measure it and can we treat it?

IF 4.8 2区医学 Q1 CLINICAL NEUROLOGY

Journal of Neurology Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI:10.1007/s00415-024-12524-9

John DeLuca

引用次数: 0

Abstract

Fatigue is a common and debilitating symptom in multiple sclerosis (MS). However, after over 100 years of inquiry its definition, measurement and understanding remains elusive. This paper describes the challenges clinicians and researchers face when assessing and treating MS patients, as well as our understanding of neural mechanisms involved in fatigue. Challenges for the future are discussed.

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多发性硬化症患者的疲劳：我们能测量它吗，我们能治疗它吗？

疲劳是多发性硬化症（MS）中常见的一种使人衰弱的症状。然而，经过 100 多年的研究，人们对其定义、测量和理解仍然难以捉摸。本文介绍了临床医生和研究人员在评估和治疗多发性硬化症患者时所面临的挑战，以及我们对疲劳所涉及的神经机制的理解。本文还讨论了未来面临的挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neurology 医学-临床神经学

CiteScore

10.00

自引率

5.00%

发文量

558

审稿时长

1 months

期刊介绍： The Journal of Neurology is an international peer-reviewed journal which provides a source for publishing original communications and reviews on clinical neurology covering the whole field. In addition, Letters to the Editors serve as a forum for clinical cases and the exchange of ideas which highlight important new findings. A section on Neurological progress serves to summarise the major findings in certain fields of neurology. Commentaries on new developments in clinical neuroscience, which may be commissioned or submitted, are published as editorials. Every neurologist interested in the current diagnosis and treatment of neurological disorders needs access to the information contained in this valuable journal.