Mycobacterium Infection of Abscess with Hemoptysis as the Initial Manifestation.

IF 0.7 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Clinical laboratory Pub Date : 2024-07-01 DOI:10.7754/Clin.Lab.2024.240209

Jingshan Bai, Wanyang Xu, Wenrui Li, Xiaoning Zhang, Kunyang Li, Yutao Zhou

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引用次数: 0

Abstract

Background: Mycobacterium abscessus is a new pathogen in recent years, which belongs to non-tuberculosis mycobacterium. Mycobacterium abscessus is widely involved in many nosocomial infections and secondary aggravation of genetic respiratory diseases. Mycobacterium abscessus is naturally resistant to most antibiotics and is difficult to treat. We report a case of mycobacterium abscessus infection with hemoptysis as the first manifestation.

Methods: Bronchoscopy, next-generation sequencing (NGS).

Results: Acid-fast staining of bronchoscopic lavage fluid showed that a small amount of acid-fast bacilli could be seen. NGS test showed the presence of Mycobacterium abscess, sequence number 137 (reference range ≥ 0), and symptomatic treatment against non-tuberculosis mycobacteria.

Conclusions: For the follow-up infection of patients with hemoptysis, the treatment effect of antibiotics is not good, so the pathological tissue should be obtained by bronchoscopy or percutaneous lung biopsy in time, and the diagnosis should be confirmed by NGS if necessary.

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以咯血为首发症状的脓肿分枝杆菌感染

背景：脓肿分枝杆菌是近年来出现的一种新病原体，属于非结核分枝杆菌。脓肿分枝杆菌广泛参与许多院内感染和遗传性呼吸道疾病的继发加重。脓肿分枝杆菌对大多数抗生素具有天然耐药性，难以治疗。我们报告了一例以咯血为首发表现的脓肿分枝杆菌感染病例：方法：支气管镜检查、新一代测序（NGS）：结果：支气管镜灌洗液的耐酸染色显示可见少量耐酸杆菌。NGS检测显示存在脓肿分枝杆菌，序列号为137（参考范围≥0），并针对非结核分枝杆菌进行了对症治疗：对于咯血患者的后续感染，抗生素治疗效果不佳，应及时通过支气管镜或经皮肺活检获取病理组织，必要时通过 NGS 确诊。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.