Association of geriatric nutritional risk index with bone mineral density and osteoporosis in postmenopausal elderly women with T2DM.

IF 1.3 4区 医学 Q4 NUTRITION & DIETETICS
Yangting Zhao, Chongyang Chen, Xiaoyu Lv, Kai Li, Yawen Wang, Dengrong Ma, Xiaohui Zan, Mei Han, Xinyuan Guo, Songbo Fu, Jingfang Liu
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引用次数: 0

Abstract

Background and objectives: To investigate the relationship between geriatric nutritional risk index (GNRI) and osteoporosis (OP) in postmenopausal elderly women with type 2 diabetes mellitus (T2DM).

Methods and study design: A total of 141 postmenopausal elderly women with T2DM was divided into OP and normal bone mineral density (BMD) groups, the differences in GRNI levels between the two groups were compared. According to the tertile levels of GRNI, T2DM were divided into three groups (T1, T2, T3 groups), and the differences in OP prevalence and levels of BMD among the three groups were compared.

Results: Among postmenopausal elderly women with T2DM, GNRI levels were lower in the OP group compared to the nor-mal BMD group [(103±5.46) vs. (105±5.46), p<0.05)]. With elevated GNRI levels, the BMD levels of femoral, total hip, total body, and lumbar vertebrae (L) were gradually increased, which were higher in the T3 group than in the T1 group (all p< 0.05). GNRI levels were positively correlated with the BMD levels of femoral, spine, total hip, total body, L1, L2, L3, L4, and L1-L4. GNRI was an independent influencing factor for the occurrence of OP (OR=0.887, 95%CI [0.795,0.988]). The ROC curve showed that the GNRI combined with serum ALP and P levels had a high predictive value for OP, with an area under the curve of 0.725 (p<0.01).

Conclusions: In postmenopausal elderly women with T2DM, GNRI was independently and positively correlated with BMD levels. GNRI may be a predictor development of OP.

患有 T2DM 的绝经后老年妇女的老年营养风险指数与骨矿物质密度和骨质疏松症的关系。
背景和目的探讨老年营养风险指数(GNRI)与2型糖尿病(T2DM)绝经后老年妇女骨质疏松症(OP)之间的关系:将141名患有T2DM的绝经后老年妇女分为骨质疏松症(OP)组和骨矿物质密度(BMD)正常组,比较两组间GRNI水平的差异。根据 GRNI 的三分位水平,将 T2DM 分成三组(T1、T2、T3 组),比较三组 OP 患病率和 BMD 水平的差异:结果:在患有T2DM的绝经后老年妇女中,OP组的GNRI水平低于无钙化BMD组[(103±5.46) vs. (105±5.46),p结论:在患有T2DM的绝经后老年妇女中,OP组的GNRI水平低于无钙化BMD组:在患有 T2DM 的绝经后老年妇女中,GNRI 与 BMD 水平呈独立正相关。GNRI可能是OP发展的一个预测因子。
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来源期刊
CiteScore
2.50
自引率
7.70%
发文量
58
审稿时长
6-12 weeks
期刊介绍: The aims of the Asia Pacific Journal of Clinical Nutrition (APJCN) are to publish high quality clinical nutrition relevant research findings which can build the capacity of clinical nutritionists in the region and enhance the practice of human nutrition and related disciplines for health promotion and disease prevention. APJCN will publish original research reports, reviews, short communications and case reports. News, book reviews and other items will also be included. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by at least two anonymous reviewers and the Editor. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as material cannot be returned. Final acceptance or rejection rests with the Editorial Board
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