Nickel-photoredox-catalyzed E- and Z-stereoconvergent coupling of alkenyl halides and phenols

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-06-25 DOI:10.1093/chemle/upae111

Sodai Nishino, Takuya Kurahashi

引用次数: 0

Abstract

Herein, we report a Ni-photoredox-catalyzed stereoconvergent coupling of phenols and alkenyl halides, which affords a Z-coupling product. Moreover, by simply changing the solvent, the reaction also provides access to the E-coupling product with high stereoselectivity. The key factor for changing the stereoisomer of the product was found to be the fluorescence lifetime of photocatalyst.

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镍光氧化催化烯基卤化物和苯酚的 E 和 Z 立体转化偶联反应

在此，我们报告了一种镍光氧化催化的苯酚与烯基卤化物的立体转化偶联反应，该反应可产生 Z 偶联产物。此外，只需改变溶剂，该反应还能以高立体选择性获得 E-偶联产物。研究发现，改变产物立体异构体的关键因素是光催化剂的荧光寿命。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.