Histological response of inflamed pulp to hydraulic calcium silicate cements in direct pulp capping: Systematic review of pulpitis models.

IF 1.3 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Australian Endodontic Journal Pub Date : 2024-07-04 DOI:10.1111/aej.12873

Sıla Nur Usta, Cangül Keskin, Burcu Pirimoğlu, Abdurrahman Aksoy

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引用次数: 0

Abstract

This systematic review aimed to compare the histological response of inflamed pulpodentinal complex to the hydraulic calcium silicate cements in experimental animal models of pulpitis. Articles that evaluated the histological response of inflamed pulp to mineral trioxide aggregate (MTA) in comparison with other restorative materials were selected and analysed in detail. The risk of bias assessment was conducted using SYRCLE's RoB tool. The GRADEpro tool was used to determine the overall quality of evidence. Out of the 2947 retrieved articles from databases, five articles fulfilled the inclusion criteria. MTA induced significantly more hard tissue formation compared to calcium hydroxide. The use of pulp-capping material containing fluocinolone acetonide and ASP/PLGA-ASP/ACP/PLLA-PLGA composite membrane was comparable. This systematic review could not demonstrate enhanced efficiency of capping materials compared to MTA. Future well-conducted animal studies are warranted for demonstrating the hard tissue formation abilities of pulp-capping materials with convenient inflammatory conditions.

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发炎牙髓对直接盖髓中硅酸钙水门汀的组织学反应：牙髓炎模型的系统回顾。

本系统综述旨在比较实验性动物牙髓炎模型中发炎牙髓牙本质复合体对硅酸钙水门汀的组织学反应。研究选取了对发炎牙髓对三氧化二铝矿物骨料（MTA）和其他修复材料的组织学反应进行评估的文章，并对其进行了详细分析。使用 SYRCLE 的 RoB 工具进行偏倚风险评估。GRADEpro工具用于确定证据的总体质量。在数据库检索到的 2947 篇文章中，有 5 篇符合纳入标准。与氢氧化钙相比，MTA诱导形成的硬组织明显更多。使用含氟西酮缩丙酮的牙髓覆盖材料和ASP/PLGA-ASP/ACP/PLLA-PLGA复合膜的效果相当。与 MTA 相比，本系统综述无法证明盖髓材料的效率更高。未来有必要开展完善的动物研究，以证明牙髓覆盖材料在方便的炎症条件下形成硬组织的能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Australian Endodontic Journal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.50

自引率

6.20%

发文量

审稿时长

>12 weeks

期刊介绍： The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues. The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses. The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.