Five new glycosides from the culms of Phyllostachys nigra var. henonis.

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-12-01 Epub Date: 2024-07-04 DOI:10.1080/10286020.2024.2366450

Bao Zhang, Hai-Hua Yuan, Jia Sun, Hang Xun, Jie Wang, Feng Qiu, Jian-Jun Wang, Xi Yao, Jin Wang, Wei Fan, Feng Tang

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引用次数: 0

Abstract

Five new glycosides, namely methyl 3-methoxybenzoate-4,5-di-O-β-D-glucopyranoside (1), (1aS,3aS,3R)-3-(4'-O-β-D-glucopyranosyl-3'-methoxyphenyl)-5,6-dioxa-bicyclo[3.3.0]octane-1-one (2), quinolin-4(1H)-one-3-O-β-D-glucopyranoside (3), 3-methoxy-propiophenone 4-O-(6'-β-D-xylopyranosyl)-β-D-glucopyranoside (4), methyl 3-methoxybenzoate 4-O-(6'-β-D-xylopyranosyl)-β-D-glucopyranoside (5), and one known compound, bambulignan B (6) were isolated from the culms of Phyllostachys nigra var. henonis. Their structures were determined using spectroscopic analysis. All compounds were evaluated for their DPPH radical scavenging activity. Compound 6 exhibited antioxidant activity with IC₅₀ value of 59.5 μM (positive control, L-ascorbic acid, IC₅₀ = 12.4 μM; 2,6-ditertbutyl-4-methyl phenol, IC₅₀ = 11.8 μM).

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从黑木耳变种秆中提取的五种新苷。

五种新苷，即 3-甲氧基苯甲酸甲酯-4,5-二-O-β-D-吡喃葡萄糖苷 (1)、(1aS,3aS,3R)-3-(4'-O-β-D-吡喃葡萄糖基-3'-甲氧基苯基)-5,6-二氧杂双环[3.3.0]辛烷-1-酮(2)、喹啉-4(1H)-酮-3-O-β-D-吡喃葡萄糖苷(3)、3-甲氧基苯丙酮 4-O-(6'-β-D-吡喃木糖基)-β-D-吡喃葡萄糖苷(4)、从 Phyllostachys nigra var. henonis 的秆中分离出了 3-甲氧基苯甲酸甲酯 4-O-(6'-β-D-xylopyranosyl)-β-D-吡喃葡萄糖苷（5）和一种已知化合物--班布利酮 B（6）。秆中分离出来。通过光谱分析确定了它们的结构。对所有化合物的 DPPH 自由基清除活性进行了评估。化合物 6 具有抗氧化活性，其 IC50 值为 59.5 μM（阳性对照 L-抗坏血酸，IC50 = 12.4 μM；2,6-二叔丁基-4-甲基苯酚，IC50 = 11.8 μM）。

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.