{"title":"Robot-assisted deep brain stimulation of the centromedian nucleus of the thalamus for generalized epilepsy: targeting and operative video.","authors":"Jason A Chen, Aaron E L Warren, John D Rolston","doi":"10.3171/2024.4.FOCVID245","DOIUrl":null,"url":null,"abstract":"<p><p>The centromedian (CM) nucleus of the thalamus is a promising target for a range of brain diseases including drug-resistant generalized and multifocal epilepsy. CM is highly connected to cortical and subcortical regions including frontoparietal/sensorimotor cortex, striatum, brainstem, and cerebellum, which are involved in some generalized epilepsy syndromes like Lennox-Gastaut syndrome (LGS). In this video, the authors describe their methodology for targeting CM for deep brain stimulation (DBS). Delineation of an optimal and consistent target will expand the efficacy of neuromodulation of CM in intractable epilepsy. The video can be found here: https://stream.cadmore.media/r10.3171/2024.4.FOCVID245.</p>","PeriodicalId":74299,"journal":{"name":"Neurosurgical focus: Video","volume":"11 1","pages":"V18"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11216415/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurosurgical focus: Video","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3171/2024.4.FOCVID245","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The centromedian (CM) nucleus of the thalamus is a promising target for a range of brain diseases including drug-resistant generalized and multifocal epilepsy. CM is highly connected to cortical and subcortical regions including frontoparietal/sensorimotor cortex, striatum, brainstem, and cerebellum, which are involved in some generalized epilepsy syndromes like Lennox-Gastaut syndrome (LGS). In this video, the authors describe their methodology for targeting CM for deep brain stimulation (DBS). Delineation of an optimal and consistent target will expand the efficacy of neuromodulation of CM in intractable epilepsy. The video can be found here: https://stream.cadmore.media/r10.3171/2024.4.FOCVID245.
丘脑中央核（CM）是治疗包括耐药性全身性癫痫和多灶性癫痫在内的一系列脑部疾病的有望靶点。CM与皮层和皮层下区域高度相连，包括前顶叶/感觉运动皮层、纹状体、脑干和小脑，这些区域涉及一些全身性癫痫综合征，如伦诺克斯-加斯豪特综合征（LGS）。在这段视频中，作者介绍了他们针对CM进行深部脑刺激（DBS）的方法。确定最佳和一致的靶点将扩大对顽固性癫痫的 CM 神经调控的疗效。视频请点击：https://stream.cadmore.media/r10.3171/2024.4.FOCVID245。
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
