Gabriela M. Albuquerque , Rebeca M. Melo , Samantha D. Coiado , Giovannia A.L. Pereira , Goreti Pereira
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引用次数: 0
Abstract
The combination of more than one clinical technique has been increasingly explored to improve imaging diagnosis, suppressing the limitations of individual procedures. Quantum dots (QDs) have been associated with paramagnetic complexes (GdDOTA) to develop optical-magnetic nanoprobes for imaging techniques. Herein, we report the preparation of bimodal nanoprobes by conjugating fluorescent QDs with GdDOTA complexes through dative bonds. These nanoprobes showed an enhancement in their emission intensity compared to bare QDs. Moreover, the nanosystems exhibited r1 values up to 69% higher than the clinical GdDOTA. Therefore, the bimodal systems demonstrated promising performance for both optical and magnetic resonance imaging, exhibiting potential as bimodal contrast agents.
期刊介绍：
Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials.
Contributions include, but are not limited to, a variety of topics such as:
• Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors
• Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart
• Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction
• Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots.
• Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing.
• Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic
• Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive
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