Frailty and biological age. Which best describes our aging and longevity?

IF 8.7 2区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Aspects of Medicine Pub Date : 2024-07-01 DOI:10.1016/j.mam.2024.101291

Judith Félix , Irene Martínez de Toda , Estefanía Díaz-Del Cerro , Mónica González-Sánchez , Mónica De la Fuente

引用次数: 0

Abstract

Frailty and Biological Age are two closely related concepts; however, frailty is a multisystem geriatric syndrome that applies to elderly subjects, whereas biological age is a gerontologic way to describe the rate of aging of each individual, which can be used from the beginning of the aging process, in adulthood. If frailty reaches less consensus on the definition, it is a term much more widely used than this of biological age, which shows a clearer definition but is scarcely employed in social and medical fields. In this review, we suggest that this Biological Age is the best to describe how we are aging and determine our longevity, and several examples support our proposal.

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虚弱和生理年龄。哪一种最能说明我们的衰老和长寿？

虚弱和生物年龄是两个密切相关的概念；不过，虚弱是一种多系统老年综合征，适用于老年受试者，而生物年龄则是一种老年学方法，用于描述每个人的衰老速度，可从成年期衰老过程的开始阶段开始使用。如果说虚弱在定义上还没有达成共识的话，那么与生物年龄相比，虚弱的使用要广泛得多，因为生物年龄的定义更加明确，但在社会和医学领域却很少使用。在这篇综述中，我们认为 "生物年龄 "是描述我们如何衰老和决定我们长寿的最佳术语，并且有几个例子支持我们的建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Aspects of Medicine 医学-生化与分子生物学

CiteScore

18.20

自引率

0.00%

发文量

审稿时长

55 days

期刊介绍： Molecular Aspects of Medicine is a review journal that serves as an official publication of the International Union of Biochemistry and Molecular Biology. It caters to physicians and biomedical scientists and aims to bridge the gap between these two fields. The journal encourages practicing clinical scientists to contribute by providing extended reviews on the molecular aspects of a specific medical field. These articles are written in a way that appeals to both doctors who may struggle with basic science and basic scientists who may have limited awareness of clinical practice issues. The journal covers a wide range of medical topics to showcase the molecular insights gained from basic science and highlight the challenging problems that medicine presents to the scientific community.