Yu-Ting Zhao, Ruo-Xin Niu, Fei Guo, Zi-Ming Zhou, Xue-Qi Zhang, Lan Peng*, Zhen-Ke Li* and Zhen Wang*,
{"title":"White Light Emissive Tetraphenylethene Molecular Cage-Based Hybrid Nanoparticles for Intracellular Long-Term Imaging","authors":"Yu-Ting Zhao, Ruo-Xin Niu, Fei Guo, Zi-Ming Zhou, Xue-Qi Zhang, Lan Peng*, Zhen-Ke Li* and Zhen Wang*, ","doi":"10.1021/acsanm.4c02083","DOIUrl":null,"url":null,"abstract":"<p >Three tetraphenylethene molecular cage-based polymers with blue, yellow, and red emission (TCPBs, TCPYs, and TCPRs) were synthesized through successive atom transfer radical polymerization (ATRP) reactions. In an aqueous solution, they exhibit aggregation-induced emission effects, resulting in blue, yellow, and red fluorescence respectively. These polymers can be combined to create stable white light emissive hybrid nanoparticles (TCPWs) through Freud resonance energy transfer (FRET) effects. The resulting TCPWs demonstrate excellent fluorescence stability and can serve as fluorescent probes for long-term intracellular imaging for as long as 10 passages (20 days), outperforming single fluorescence emissive probes.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3000,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Nano Materials","FirstCategoryId":"88","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsanm.4c02083","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Three tetraphenylethene molecular cage-based polymers with blue, yellow, and red emission (TCPBs, TCPYs, and TCPRs) were synthesized through successive atom transfer radical polymerization (ATRP) reactions. In an aqueous solution, they exhibit aggregation-induced emission effects, resulting in blue, yellow, and red fluorescence respectively. These polymers can be combined to create stable white light emissive hybrid nanoparticles (TCPWs) through Freud resonance energy transfer (FRET) effects. The resulting TCPWs demonstrate excellent fluorescence stability and can serve as fluorescent probes for long-term intracellular imaging for as long as 10 passages (20 days), outperforming single fluorescence emissive probes.
期刊介绍:
ACS Applied Nano Materials is an interdisciplinary journal publishing original research covering all aspects of engineering, chemistry, physics and biology relevant to applications of nanomaterials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important applications of nanomaterials.