White Light Emissive Tetraphenylethene Molecular Cage-Based Hybrid Nanoparticles for Intracellular Long-Term Imaging

IF 5.3 2区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY
Yu-Ting Zhao, Ruo-Xin Niu, Fei Guo, Zi-Ming Zhou, Xue-Qi Zhang, Lan Peng*, Zhen-Ke Li* and Zhen Wang*, 
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引用次数: 0

Abstract

Three tetraphenylethene molecular cage-based polymers with blue, yellow, and red emission (TCPBs, TCPYs, and TCPRs) were synthesized through successive atom transfer radical polymerization (ATRP) reactions. In an aqueous solution, they exhibit aggregation-induced emission effects, resulting in blue, yellow, and red fluorescence respectively. These polymers can be combined to create stable white light emissive hybrid nanoparticles (TCPWs) through Freud resonance energy transfer (FRET) effects. The resulting TCPWs demonstrate excellent fluorescence stability and can serve as fluorescent probes for long-term intracellular imaging for as long as 10 passages (20 days), outperforming single fluorescence emissive probes.

Abstract Image

用于细胞内长期成像的白光发射四钌分子笼基混合纳米粒子
通过连续原子转移自由基聚合(ATRP)反应,合成了三种具有蓝色、黄色和红色发射的四苯基乙烯分子笼基聚合物(TCPBs、TCPYs 和 TCPRs)。在水溶液中,它们表现出聚集诱导的发射效应,分别产生蓝色、黄色和红色荧光。通过弗洛伊德共振能量转移(FRET)效应,这些聚合物可以组合成稳定的白光发射混合纳米粒子(TCPW)。由此产生的 TCPWs 具有出色的荧光稳定性,可作为荧光探针进行长达 10 个通道(20 天)的细胞内长期成像,其性能优于单一荧光发射探针。
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来源期刊
CiteScore
8.30
自引率
3.40%
发文量
1601
期刊介绍: ACS Applied Nano Materials is an interdisciplinary journal publishing original research covering all aspects of engineering, chemistry, physics and biology relevant to applications of nanomaterials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important applications of nanomaterials.
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