From frozen to feeding: storage characteristics of banked donor human milk used in a single level IV academic neonatal intensive care unit.

Research square Pub Date : 2024-06-13 DOI:10.21203/rs.3.rs-4486977/v1

Katherine Chetta, Mary Galemmo, Terence Camilon, Wrenn Tiernan, Whitney Savino, Allison Rohrer, John Baatz, Carol Wagner

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Abstract

Background: The storage time of banked donor human milk (DHM) administered in an academic hospital to critically ill preterm neonates was previously unknown.

Objective: This study was designed to determine the storage time of banked DHM by measurements obtained at the hospital level (by lot finish date) and individual patient level (by feeding date) over 2-year observation period.

Results: Both methods of measuring storage time (hospital-level and patient-level) showed that DHM was stored on average 8 ±1 months before use. Variations in storage time fluctuated across months with a minimum and maximum storage duration of 119 to 317 days. Most infants received a median of 3 [2-5 IQR] unique lots of DHM.

Conclusion: The storage time of DHM was successfully measured. Over 95% of DHM received was stored longer than 6 months. Storage times varied widely, uncovering a potential area of future research.

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从冷冻到喂养：一个四级学术新生儿重症监护室使用的银行捐赠母乳的储存特性。

背景：一家学术医院为重症早产新生儿提供的银行捐赠人乳（DHM）的储存时间以前并不清楚。研究目的本研究旨在通过对医院层面（按批次完成日期）和患者个体层面（按喂养日期）在两年观察期内的测量，确定库存供体人乳的储存时间。结果：两种测量储存时间的方法（医院层面和患者层面）均显示，DHM 在使用前平均储存 8 ± 1 个月。储存时间在各月之间波动，最短和最长储存时间分别为 119 天和 317 天。大多数婴儿收到的 DHM 的中位数为 3 [2-5 IQR] 个独特批次。结论：成功测量了 DHM 的储存时间。超过 95% 的 DHM 储存时间超过 6 个月。储存时间差异很大，这也是未来研究的一个潜在领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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